Preoperative Multimorbidity and Functional Recovery After Total Knee Arthroplasty

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, single-center observational cohort study enrolling about 230 adults undergoing elective unilateral primary total knee arthroplasty for knee osteoarthritis. Preoperative multimorbidity burden will be measured with the Functional Comorbidity Index and patients will be followed to 12 months postoperatively. Functional outcomes, pain, and patient-reported measures (WOMAC and OKS) will be collected preoperatively, at 6 months, and at 12 months, along with assessments of anxiety and depression (HADS). The goal is to determine if higher preoperative comorbidity burden is associated with poorer functional recovery after surgery. Results may help identify patients at risk for slower recovery and inform prehabilitation strategies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18 years or older.
* Scheduled for elective unilateral primary total knee arthroplasty due to primary knee osteoarthritis.
* Sufficient cognitive and communication abilities to understand and complete the study questionnaires.
* Provision of written informed consent for study participation.

Exclusion Criteria:

* Patients scheduled for revision total knee arthroplasty.
* Patients scheduled for simultaneous bilateral total knee arthroplasty.
* Arthroplasty indicated for inflammatory arthritis, tumor, infection, or post-traumatic conditions.
* Severe cognitive impairment, advanced dementia, or communication difficulties preventing valid completion of the study questionnaires.
* Significant logistical or legal circumstances preventing completion of the planned follow-up assessments.

Where it's running

• Güneş Sarikaya
  Balıkesir, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Güneş SARIKAYA — Balikesir Ataturk City Hospital
• Study coordinator: Güneş SARIKAYA
• Email: gunessarikaya05@hotmail.com
• Phone: 05436733113

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.