Pregnancy in women with rare vascular diseases

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to gather data on the obstetrical complications faced by women with rare vascular genetic disorders during pregnancy. It focuses on conditions such as Hereditary Hemorrhagic Telangiectasia, Marfan syndrome, and primary lower limb lymphedema. By collecting information through questionnaires, the study seeks to improve understanding and management of risks associated with these conditions in pregnant women. The ultimate goal is to formulate evidence-based recommendations to enhance maternal and fetal health outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Women aged ≥ 18 years and ≤45 years at the time of inclusion
* Pregnant and/or having given birth less than 1 month (≤ 30 days)
* Clinically and/or radiological and/or molecular biology diagnosis of a rare vascular disease before or during pregnancy or one month after delivery.
* Having been informed of all pertinent aspects of the study and provided oral non-opposition.

Exclusion Criteria:

* Any person not fulfilling the inclusion criteria or refusing to take part in the study.
* Major under legal protection

Where it's running

• Service de Médecine Interne et Maladies Vasculaires + Service Neuropédiatrie et neurochirurgie de l'enfant - CHU Angers
  Angers, France Recruiting
• Service Pneumologie et Oncologie Thoracique - AP-HP Hôpital Ambroise Paré
  Boulogne-Billancourt, France Recruiting
• Centre de Référence pour la maladie de Rendu-Osler - Service Génétique Clinique - Hôpital Femme-Mère-Enfant - Hospices Civils de Lyon
  Bron, France Recruiting
• Service d'Imagerie Pédiatrique et Fœtale et Consultation Pluridisciplinaire des Angiomes - Hôpital Femme-Mère-Enfant - HCL
  Bron, France Recruiting
• Service de Génétique, Hôpital Femme-Mère-Enfant
  Bron, France Recruiting
• Service de Médecine Vasculaire - Hôpital de la Côte de Nacre
  Caen, France Recruiting

Study contacts

• Principal investigator: Sophie DUPUIS-GIROD, MD — Service de Génétique - Hôpital Femme-Mère-Enfant - HCL
• Study coordinator: Sophie DUPUIS-GIROD, MD
• Email: sophie.dupuis-girod@chu-lyon.fr
• Phone: 04 27 85 65 25

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.