Clinical trial Recruiting at 5 sites Observational Ages 18 to 80

Predicting tooth wear using advanced scanning techniques

Official title: Prediction of the Tooth Wear Index Based on a Dataset of Dental Shapes:a Retrospective Study

Run by Hospices Civils de Lyon · NCT06681844 · Data updated 2026-11-12

This study is testing a new scanning method to see if it can help predict tooth wear early on, so people can take better care of their teeth before serious damage happens.

Quick facts

Study typeObservational
Ages18 Years to 80 Years
SexAll
Enrollment1000 (estimated)
SponsorHospices Civils de Lyon
Academic / other
Locations5 sites (Indianapolis, Indiana and 4 other locations)
StatusRecruiting
StartedDecember 12, 2023
Main results expectedDecember 12, 2025
Study endsDecember 2027
Registry record updatedNovember 8, 2024
Trial IDNCT06681844 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients with avulsed mature incisors, canines, premolars, or molars that exhibit a tooth wear index between 0 and 3.

Probably not a fit

Patients with teeth that have a wear index over 3 or those with immature teeth or wisdom teeth will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on predicting tooth wear, which is the gradual loss of dental hard tissue due to various factors. It utilizes intraoral scanners to monitor changes in tooth shape, aiming for early detection of wear that is often overlooked until it becomes severe. The study employs a novel method called MEG-IsoQuad, which automates the remeshing process to enhance the reliability of statistical shape analysis for diagnosing tooth wear. By assessing avulsed teeth with a specific wear index, the study seeks to improve understanding and management of tooth wear.

Why it matters

Potential benefit: If successful, this approach could lead to earlier detection and better management of tooth wear, ultimately improving patients' oral health and quality of life.

How similar studies have gone: While the use of statistical shape analysis in dentistry is emerging, this specific combination of automated remeshing and shape analysis is relatively novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* teeth avulsed presenting a tooth wear index between 0 and 3
* mature incisor, canine, premolar or molars (1st and 2nd only)

Exclusion Criteria:

* teeth avulsed presenting a tooth wear index over 3 (or presenting an oral rehabilitation representative of a similar wear)
* immature teeth or teeth without root edification
* wisdom teeth

Where it's running

  • Indiana University Hospital
    Indianapolis, Indiana, United States
    Recruiting
  • KU Leuven University Hospital
    Leuven, Belgium
    Recruiting
  • Lyon Dental Hospital
    Lyon, France
    Recruiting
  • King George Medical University
    Lucknow, India
    Recruiting
  • Tel Aviv Universi
    Tel Aviv, Israel
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.