Predicting outcomes for patients with ischemic stroke from large-artery atherosclerosis
Official title: A Prospective Observational Cohort Study of Predictive Factors Related to Prognosis of In-hosiptal Patients With Ischemic Stroke Due to Large-artery Atherosclerosis
Run by Tongji Hospital · NCT04847752 · Data updated 2026-11-12
This study is trying to find out what factors can help predict how well people with ischemic stroke from large-artery atherosclerosis will recover.
Quick facts
| Study type | Observational |
|---|---|
| Ages | Any age to 80 Years |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | Tongji Hospital Academic / other |
| Locations | 1 site (Wuhan) |
| Status | Recruiting |
| Started | March 1, 2021 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2028 |
| Registry record updated | June 20, 2024 |
| Trial ID | NCT04847752 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients diagnosed with ischemic stroke due to large-artery atherosclerosis with specific stenosis criteria.
✕Probably not a fit
Patients with cerebral hemorrhage or severe systemic diseases expected to survive less than three months may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to identify predictive factors related to the prognosis of patients suffering from ischemic stroke due to large-artery atherosclerosis. Conducted at Tongji Hospital, it will recruit 1000 patients from March 2021 to December 2026, collecting detailed clinical data and assessing stroke severity using the NIHSS and mRS scales. The study will utilize various imaging techniques and blood tests to analyze in-hospital factors that may influence patient outcomes, ultimately providing evidence-based treatment suggestions.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of prognosis in ischemic stroke patients, leading to improved treatment strategies.
How similar studies have gone: Other studies have shown promise in identifying prognostic factors in ischemic stroke, suggesting that this approach may yield valuable insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Ischemic stroke due to large-artery atherosclerosis has been proved by clinical symptoms and imaging examinations. * Symptomatic superior arch stenosis \>50% * Asymptomatic superior arch stenosis was \>70% * written informed consent was obtained from patients or their surrogates before enrollment. Exclusion Criteria: * Brain CT or MRI showing cerebral hemorrhage (excluded ischemic stroke with hemorrhage transformation) * With severe systemic disease, are expected to survive \< 3 months * Patients will not able to provide continuous follow-up information
Where it's running
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Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, China Recruiting
Study contacts
- Principal investigator: Chuan Qin, Dr. — Tongji Hospital
- Study coordinator: Dai-Shi Tian, Dr.
- Email: tiands@tjh.tjmu.edu.cn
- Phone: 86-27-83663337
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.