Predicting early mobility after hip or knee replacement using a machine learning model
Official title: Development and Pre-validated Multiple Variable Prediction Model Using Machine Learning for Early Functional Recovery After Joint Replacement Surgery.
Run by Istituto Ortopedico Rizzoli · NCT07333560 · Data updated 2026-11-12
A machine learning model is being tested to see if it can predict which patients will walk sooner after hip or knee replacement surgery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 943 (estimated) |
| Sponsor | Istituto Ortopedico Rizzoli Academic / other |
| Locations | 2 sites (Bologna and 1 other locations) |
| Status | Recruiting |
| Started | March 9, 2026 |
| Main results expected | December 2027 |
| Study ends | December 2027 |
| Registry record updated | June 1, 2026 |
| Trial ID | NCT07333560 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18 years or older who had elective hip or knee arthroplasty and started postoperative physiotherapy.
✕Probably not a fit
Patients with atypical recovery patterns not captured by the model or those without postoperative physiotherapy may see limited benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study develops and pre-validates a predictive model using retrospective data from 2020-2023 and prospective data from 2026-2027. It combines clinical and perioperative information to forecast early mobility recovery and length of hospital stay after elective arthroplasty. The model will be trained on past data and prospectively tested in routine care, using multiple algorithms and standard performance metrics. Predictors include demographics, surgery and anesthesia details, physiotherapy timing, pain, catheter use, and orthostatic intolerance. Outcomes focus on ability to climb stairs in the first four days and discharge by day five.
Why it matters
Potential benefit: If successful, the model could help tailor postoperative planning and resource use for patients undergoing hip or knee replacement.
How similar studies have gone: Prior predictive modeling in orthopedic recovery has shown promise, but this exact approach for early mobility and length of stay in arthroplasty is being tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 18 years or older * Patients underwent elective hip or knee arthroplasty. * Patients for whom postoperative physiotherapy was initiated. Exclusion Criteria: * Patients who underwent surgery for oncologic disease, femoral fracture, or revision joint arthroplasty. * Patients for whom postoperative physiotherapy was not provided due to postoperative complications * clinical data are unavailable.
Where it's running
-
SAITeR IRCCS Istituto Ortopedico Rizzoli
Bologna, Italy Recruiting -
Azienda U.S.L. - IRCCS di Reggio Emilia
Reggio Emilia, Italy Not yet recruiting
Study contacts
- Principal investigator: Mattia Morri — IRCCS Istotuto Ortopedico Rizzoli
- Study coordinator: Mattia Morri
- Email: mattia.morri@ior.it
- Phone: +390516366694
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.