Pre-operative rehabilitation for patients with limb sarcoma

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This Phase II interventional study aims to evaluate the effectiveness of a pre-operative rehabilitation program for patients diagnosed with bone or soft-tissue sarcoma in the limbs. The program involves a multidisciplinary team, including rehabilitation doctors, physiotherapists, occupational therapists, specialized nurses, dieticians, and adapted physical activity instructors, to enhance functional recovery and patient autonomy post-surgery. Patients will be monitored for up to 24 months following their surgical intervention to assess outcomes related to their rehabilitation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age \> or = 16 years old.
2. Patient with a diagnosis of bone or soft-tissue sarcoma confirmed by the "Réseau de Relecture en Pathologie Sarcomateuse (RRePS)"
3. Tumour localized in the lower or upper limb.
4. Localized or metastatic disease (in case of metastatic disease, the optimal surgical treatment for the primary tumor must be performed).
5. Indication of neoadjuvant treatment (radiotherapy and/or chemotherapy) according to the Multidisciplinary Concertation Meeting.
6. Inclusion before the initiation or during neoadjuvant treatment. In both cases, surgery must be scheduled between 6 and 10 weeks after inclusion, to permit the completion of the surgical prehabilitation.
7. Patient must provide written informed consent prior to any study-specific procedure. For minor patients, the holder(s) of parental authority must sign the informed consent and the patient's assent must be obtained.
8. Patient affiliated to the French social security system.

Exclusion Criteria:

1. Metastatic disease without optimal surgery planned of the primary tumour.
2. Any disease or medical condition that could interfere with study procedure, or that could, according to the judgment of investigator, expose the patient to an unacceptable risk.
3. Patient who has forfeited his/her freedom by administrative or legal award or who is under legal protection (curatorship and guardianship, protection of justice).
4. Any psychological, familial, geographic or social situation preventing compliance with the medical monitoring and/or with study procedure.
5. Pregnant or breastfeeding patient.

Where it's running

• Institut Universitaire du Cancer de Toulouse - Oncopole
  Toulouse, France Recruiting

Study contacts

• Study coordinator: Dimitri GANGLOFF
• Email: gangloff.dimitri@iuct-oncopole.fr
• Phone: 05 31 15 53 58

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.