Clinical trial Recruiting at 1 site Interventional Ages 18 to 64

Infiltration with ropivacaine plus triamcinolone to relieve pain after VATS surgery

Official title: The Efficacy and Safety of Pre-incisional Infiltration With Ropivacaine Plus Triamcinolone in Patients Undergoing Video-assisted Thoracoscopic: a Multi-center Randomized Controlled Trial.

Run by Beijing Tiantan Hospital · NCT07603921 · Data updated 2026-11-12

This study tests whether injecting ropivacaine with or without triamcinolone before incision can reduce pain after thoracoscopic lung surgery in adults.

More Segmentectomy trials

Quick facts

Study typeInterventional
Ages18 Years to 64 Years
SexAll
Enrollment346 (estimated)
SponsorBeijing Tiantan Hospital
Academic / other
Locations1 site (Beijing, Beijing Municipality)
StatusRecruiting
StartedSeptember 1, 2026
Main results expectedMay 31, 2027
Study endsMarch 31, 2028
Registry record updatedSeptember 17, 2026
Trial IDNCT07603921 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18-64 scheduled for elective VATS lung procedures (wedge resection, segmentectomy, or lobectomy) with ASA I–III, able to consent and participate in follow-up.

Probably not a fit

Patients who are allergic to opioids, steroids, or local anesthetics, those with significant organ dysfunction, or those unable to complete pain assessments may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study examines pre-incisional infiltration of local anesthetic agents to reduce postoperative pain after video-assisted thoracoscopic surgery for lung procedures. Participants are adults (18-64) undergoing wedge resection, segmentectomy, or lobectomy who are ASA I–III. The trial compares ropivacaine with triamcinolone versus ropivacaine alone, aiming to see if the combination provides superior analgesia and improves recovery. Outcomes focus on pain control in the immediate perioperative period and early postoperative recovery. The study is conducted at Beijing Tiantan Hospital with the aim of informing analgesia practices for VATS procedures.

Why it matters

Potential benefit: If successful, patients may experience less postoperative pain and faster recovery after VATS lung surgery.

How similar studies have gone: Previous approaches using regional/local analgesia for thoracic surgery have shown reduced pain, but this exact combination (ropivacaine plus triamcinolone vs ropivacaine alone) is less established.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients scheduled for elective thoracoscopic wedge resection, segmentectomy, and lobectomy under general anesthesia;
2. Ages 18 to 64 years old
3. American Society of Anesthesiologists (ASA) physical status of I-III
4. Patients must be able to understand nature and potential personal consequences of the clinical trial and cooperation with follow-up investigations
5. signing of the informed consent form.

Exclusion Criteria:

1. History of allergies to experimental drugs such as opioids or steroids;
2. Alcohol abuse; Long term use of opioid drugs (exceeding 2 weeks or 3 days per week for more than 1 month); Suspected use of sedatives and analgesics; Use analgesic drugs within 24 hours before surgery; Patients undergoing steroid therapy;
3. Serious neurological disorders, severe liver and kidney dysfunction, heart failure, etc;
4. Unable to use pain assessment scale;
5. Pregnant or lactating patients.

Where it's running

  • Beijing Tiantan Hospital
    Beijing, Beijing Municipality, China
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.