Post-operative pain after stabilizing free gingival grafts using titanium tacks vs sutures around natural teeth
Official title: Clinical Evaluation of Titanium Tacks Used for the Stabilization of Free Gingival Graft in Gingival Augmentation Around Natural Teeth: A Randomized Controlled Clinical Trial
Run by Cairo University · NCT07655349 · Data updated 2026-11-12
This trial tests whether using titanium tacks to stabilize free gingival grafts causes less post-operative pain than traditional sutures in adults needing gum tissue augmentation.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 24 (estimated) |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo, Cairo Governorate) |
| Status | Recruiting |
| Started | March 17, 2025 |
| Main results expected | February 1, 2027 |
| Study ends | July 1, 2027 |
| Registry record updated | June 17, 2026 |
| Trial ID | NCT07655349 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18 years or older requiring an FGG around natural teeth with keratinized tissue width under 2 mm, good oral hygiene, and the ability to cooperate.
✕Probably not a fit
Patients with poor oral hygiene, pregnancy, smoking, or conditions that compromise healing may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study compares two methods for stabilizing free gingival grafts around natural teeth: titanium tacks versus standard suturing. It aims to determine if titanium tacks reduce post-operative pain and to evaluate effects on clinical outcomes such as keratinized tissue width, gingival thickness, graft size, procedure time, plaque accumulation, and daily activity interference. Eligible participants are adults with keratinized tissue width less than 2 mm undergoing FGG and maintaining good oral hygiene. The study is conducted at Cairo University’s Faculty of Dentistry and Oral Medicine under the lead sponsor Karim Abdelrahim Mohamed Abdelsamad. Timely findings could influence graft stabilization practices in periodontal surgery.
Why it matters
Potential benefit: If successful, patients may experience less post-operative pain and comparable or improved graft outcomes with titanium tacks.
How similar studies have gone: Prior work in periodontal graft stabilization with alternative fixation methods suggests potential benefits, but this exact comparison is novel for this context.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients age 18 years or older. 2. Patients with healthy systemic condition. 3. Indication for FGG treatment (i.e., difficulty or discomfort during oral hygiene; gingival margin mobility; high muscle attachment and/or frenum pull; shallow vestibule and gingival recession) around natural teeth. 4. Keratinized tissue width (KTW) \< 2 mm. 5. Good oral hygiene. 6. Cooperative patients. Exclusion Criteria: 1. Pregnant females. 2. Smokers: a contraindication for any plastic periodontal surgery. 3. Unmotivated and uncooperative patients with poor oral hygiene. 4. Patients with habits that may compromise the longevity and affect the result of the study as parafunctional habits. 5. Patients who have undergone periodontal surgery in the same area within 6 months.
Where it's running
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Faculty of Dentistry and Oral Medicine, Cairo University, Cairo.
Cairo, Cairo Governorate, Egypt Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.