Clinical trial Recruiting at 1 site Interventional Ages 18 to 40

Plyometric training added to standard rehab after ACL reconstruction

Official title: The Effect of Adding Plyometric Training to Rehabilitation Program in Post-ACL Reconstruction Surgery

Run by Cairo University · NCT07862881 · Data updated 2026-11-12

This study tests whether adding plyometrics to the usual rehab after ACL reconstruction helps improve leg strength and function in adults aged 18–40.

Quick facts

Study typeInterventional
Ages18 Years to 40 Years
SexAll
Enrollment40 (estimated)
SponsorCairo University
Academic / other
Locations1 site (Qina, Qena Governorate)
StatusRecruiting
StartedOctober 1, 2026
Main results expectedApril 1, 2027
Study endsMay 1, 2027
Registry record updatedOctober 15, 2026
Trial IDNCT07862881 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18–40 who have had a primary unilateral ACL reconstruction with BPTB or hamstring autografts and are cleared for progressive resistance and functional training.

Probably not a fit

Individuals who are not able to perform plyometric exercises or who have contraindications to high-impact training may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized trial compares two rehabilitation strategies after ACL reconstruction. One group follows a standard 24-week rehab program, while the second group starts with the same standard program for 16 weeks and then adds a plyometric training phase for 8 weeks, totaling 24 weeks. The goal is to see if plyometrics improves muscular strength, dynamic balance, and functional performance. Eligible participants are adults 18–40 with primary unilateral ACL reconstruction using BPTB or hamstring autografts, cleared for progressive resistance training, and able to bear weight without aids. Outcomes focus on strength, proprioception, balance, and function, measured through objective tests and performance metrics.

Why it matters

Potential benefit: If successful, the approach could enhance recovery and return-to-sport outcomes after ACL reconstruction.

How similar studies have gone: Previous work suggests plyometrics can improve strength and functional performance after knee injuries, but evidence specific to ACLR rehabilitation varies by protocol.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Age 18-40 years
2. Primary unilateral ACL reconstruction
3. Reconstruction using bone-patellar tendon-bone (BPTB) or hamstring tendon (HT) autograft
4. Cleared by operating surgeon for progressive resistance and functional training
5. Able to perform full weight-bearing ambulation without assistive devices

Exclusion Criteria:

1. Revision ACL reconstruction
2. Associated grade III ligament injury
3. Meniscal repair (meniscectomy is not an exclusion)
4. Concomitant chondral defect requiring surgical intervention or cartilage repair
5. Contralateral lower limb injury within the preceding 12 months
6. Body mass index (BMI) \> 35 kg/m²

Where it's running

  • PTOC South Valley University
    Qina, Qena Governorate, Egypt
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.