Clinical trial Recruiting at 1 site Interventional Ages 18 to 40

Isokinetic vs Plyometric Training After ACL Reconstruction

Official title: The Effects of Isokinetic Training Versus Plyometric Training Post ACL Reconstruction

Run by Cairo University · NCT07862868 · Data updated 2026-11-12

This trial tests whether isokinetic or plyometric training, added after standard rehab, best improves strength, function, and patient-reported outcomes in adults 18–40 after ACL reconstruction.

Quick facts

Study typeInterventional
Ages18 Years to 40 Years
SexAll
Enrollment40 (estimated)
SponsorCairo University
Academic / other
Locations1 site (Qina, Qena Governorate)
StatusRecruiting
StartedOctober 1, 2026
Main results expectedJanuary 1, 2027
Study endsFebruary 1, 2027
Registry record updatedOctober 15, 2026
Trial IDNCT07862868 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18–40 who have had a primary unilateral ACL reconstruction using BPTB or hamstring autografts and are cleared for progressive resistance and functional training.

Probably not a fit

Individuals with revision ACL procedures, complex concomitant knee injuries, significant cartilage disease requiring intervention, recent contralateral knee injury, or BMI above 35 kg/m² may not benefit or may be excluded from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults aged 18–40 who have had a primary unilateral ACL reconstruction are randomized to two 24-week training programs after 16 weeks of standard rehabilitation: isokinetic training versus plyometric training. The study aims to compare effects on muscular strength, functional performance, and patient-reported outcomes, with no anticipation that one method will be superior. Both groups follow the same rehabilitation before the specific training phase. The trial uses standard outcome measures relevant to return-to-sport criteria and overall knee function. This randomized comparison addresses a gap where direct, head-to-head data on these two commonly used post-ACL rehab approaches are limited.

Why it matters

Potential benefit: If one method proves superior, patients could receive more effective guidance for rehabilitation after ACL reconstruction to improve strength and function.

How similar studies have gone: Previous evidence supports both isokinetic and plyometric training post-ACL reconstruction, but direct head-to-head randomized comparisons on comprehensive outcomes are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Age 18-40 years
2. Primary unilateral ACL reconstruction
3. Reconstruction using bone-patellar tendon-bone (BPTB) or hamstring tendon (HT) autograft
4. Cleared by operating surgeon for progressive resistance and functional training
5. Able to perform full weight-bearing ambulation without assistive devices

Exclusion Criteria:

1. Revision ACL reconstruction
2. Associated grade III ligament injury
3. Meniscal repair (meniscectomy is not an exclusion)
4. Concomitant chondral defect requiring surgical intervention or cartilage repair
5. Contralateral lower limb injury within the preceding 12 months
6. Body mass index (BMI) \> 35 kg/m²

Where it's running

  • PTOC South Valley University
    Qina, Qena Governorate, Egypt
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.