Muscle Power After ACL Reconstruction: How Knee Extensor Strength Relates to Function
Official title: Muscle Function Following Anterior Cruciate Ligament Reconstruction: Impaired Power Output in Physically Active Individuals
Run by Centre Hospitalier Metropole Savoie · NCT07765173 · Data updated 2026-11-12
This study tests whether changes in knee extensor strength and power after ACL reconstruction are linked to how well patients function in daily life, up to 24 months post-surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 110 (estimated) |
| Sponsor | Centre Hospitalier Metropole Savoie Academic / other |
| Locations | 1 site (Challes-les-Eaux) |
| Status | Recruiting |
| Started | June 8, 2026 |
| Main results expected | June 8, 2030 |
| Study ends | June 8, 2030 |
| Registry record updated | August 14, 2026 |
| Trial ID | NCT07765173 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Physically active individuals (Tegner ≥ 4) undergoing isolated or complex ACL reconstruction who have no prior ipsilateral knee surgery and can comply with study procedures.
✕Probably not a fit
Patients with recurrent ACL rupture, multi-ligament injuries, or comprehension difficulties may not benefit from the study outcomes.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The trial assesses objective knee extensor strength and power before ACL reconstruction and at 3, 6 months, with patient-reported function measured by IKDC-SKF. It uses force-velocity and power-velocity tests during cycling and knee extensions, plus isometric strength assessments. Correlations between physical measures and patient function will be analyzed to understand recovery patterns in physically active individuals. Participants include patients undergoing isolated or complex ACL reconstruction and will be followed for up to two years. The study is conducted at Medipôle de Savoie with support from Université Savoie Mont Blanc.
Why it matters
Potential benefit: If successful, the findings could help tailor rehabilitation to improve both objective knee function and patient-perceived outcomes after ACL reconstruction.
How similar studies have gone: Previous work in ACL rehabilitation has shown links between muscle function and functional outcomes, but this study adds detailed force-velocity profiling and longer follow-up in an active population.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients requiring isolated or complex ACL reconstruction (combined with a meniscal injury) * Patients who are physically active (Tegner score ≥ 4) and wish to resume such activity. * Patients with no history of surgery on the ipsilateral knee (i.e., native knee). * Patients able to comply with the study procedures * Patients who have given their free and informed written consent, having been informed of the purpose of the study, its procedure and its risks. * Be affiliated to a social security scheme. Exclusion Criteria: * Patient with comprehension difficulties * Recurrent rupture of the ipsilateral ACL * Multi-ligament injuries (i.e., injury to the medial collateral ligament, lateral collateral ligament or posterior cruciate ligament)
Where it's running
-
Médipôle de Savoie
Challes-les-Eaux, France Recruiting
Study contacts
- Study coordinator: leo blervaque
- Email: leo.blervaque@ch-metropole-savoie.fr
- Phone: 04.79.96.58.13
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Plyometric training added to standard rehab after ACL reconstruction
This study tests whether adding plyometrics to the usual rehab after ACL reconstruction helps improve leg strength and function in adults aged 18–40.
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Isokinetic vs Plyometric Training After ACL Reconstruction
This trial tests whether isokinetic or plyometric training, added after standard rehab, best improves strength, function, and patient-reported outcomes in adults 18–40 after ACL reconstruction.
-
Methylprednisolone taper plus standard pain medicines after ACL repair
We will try adding a methylprednisolone dose-pack to usual pain medicines after ACL repair to see if it lowers pain and reduces opioid use for people aged 13 to 50.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.