PhenoAgeAccel: Can a Biological Age Marker Predict Disease and Mortality in Chinese Adults?

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational study conducted at the Second Affiliated Hospital of Nanchang University in China. It analyzes existing routine blood test data to calculate Phenotypic Age and PhenoAgeAccel, then follows participants to see if higher PhenoAgeAccel links to greater risk of developing major chronic diseases, all-cause mortality, and shorter disease-free life expectancy. No interventions are given; researchers rely on medical records and database linkage to track outcomes. Eligible adults are 35–73 years old with complete baseline data and consent for data use, while exclusion criteria remove those with end-stage illnesses or missing essential data. The goal is to understand whether a biological aging marker can help predict health trajectories in this population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 35-73 years old. Complete routine blood test data available at baseline to calculate Phenotypic -Age (including albumin, alkaline phosphatase, creatinine, glucose, C-reactive protein, lymphocyte percentage, mean corpuscular volume, red cell distribution width, and white blood cell count).

Complete demographic and clinical data (e.g., sex, BMI, comorbidities) available at baseline.

* Consent to use routine medical data for research follow-up analysis.

Exclusion Criteria:

* Presence of end-stage diseases (e.g., end-stage liver/renal failure) other than the major chronic diseases of interest at baseline.
* Key baseline data missing, making Phenotypic Age calculation impossible. Incomplete follow-up information or inability to confirm outcomes (e.g., death, disease onset) via database linkage.
* Refusal to participate in the study or withdrawal of informed consent.

Where it's running

• Second Affiliated Hospital of Nanchang University
  Nanchang, Jiangxi, China Recruiting

Study contacts

• Study coordinator: Xi-jian Dai, Doctor
• Email: daixjdoctor@126.com
• Phone: 13755756959

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.