Perioperative care and outcomes for older adults having surgery
Elderly Patients Undergoing Surgery During Perioperative Period: a Prospective Cohort Study
This project will follow people aged 65 and older who are having surgery to try to identify clinical and biological factors that raise the risk of postoperative delirium and other complications.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1200 (estimated) |
| Ages | 65 Years and up |
| Sex | All |
| Sponsor | Second Affiliated Hospital of Wenzhou Medical University Academic / other |
| Locations | 1 site (Wenzhou, Zhejiang) |
| Trial ID | NCT07314762 on ClinicalTrials.gov |
What this trial studies
This is a prospective cohort study enrolling patients aged 65 or older at a single medical center and collecting clinical data and biological samples across the perioperative period. Samples and standardized clinical information will be obtained before, during, and after surgery to capture changes linked to complications. Investigators will monitor patients for postoperative delirium, other complications, length of stay, and short-term outcomes. The collected data will be used to explore possible mechanisms and to build a risk prediction model for postoperative complications in older surgical patients.
Who should consider this trial
Good fit: Ideal candidates are people aged 65 or older treated at the participating hospitals who agree to provide informed consent and perioperative clinical information and biological samples.
Not a fit: People younger than 65 or those who refuse consent or sampling will not be eligible and therefore will not receive direct benefit from participation.
Why it matters
Potential benefit: If successful, the work could help clinicians identify high-risk older patients earlier and target preventive measures to reduce delirium and other postoperative complications.
How similar studies have performed: Previous cohort studies have identified some risk factors and produced predictive models for postoperative delirium, so this work builds on an existing but still-improving evidence base.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1\) Surgical patients aged 65 or above or non-surgical subjects aged 65 or above. 2) Agree to participate in this study and sign the informed consent form. Exclusion Criteria: 1）Refused to participate in the study.
Where this trial is running
Wenzhou, Zhejiang
- The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University — Wenzhou, Zhejiang, China (Recruiting)
Study contacts
- Principal investigator: Ting Li, MD. PhD — Department of Anaesthesiology and Perioperative Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China
- Study coordinator: Ting Li MD. PhD
- Email: liting1021@aliyun.com
- Phone: +86-135-8787-6896
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.