Peripheral Venous Pressure–Guided Care in Heart Failure

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This intervention compares standard clinical care to care guided by daily peripheral venous pressure measurements in hospitalized heart failure patients with acute decompensation. Researchers will track length of stay, 30-day rehospitalization, and 6-month rehospitalization, along with symptoms, lab values, diuretic use, and imaging needs. The study is conducted at Aurora St. Luke's Medical Center and led by Wake Forest University Health Sciences. It is an interventional study without a specified phase. Participation requires an existing IV line and English-speaking status, among other safety criteria.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with minimum 3-month history of Congestive Heart Failure admitted to Aurora St. Luke's Medical Center with acute decompensation
* English speaking only

Exclusion Criteria:

* Patients who do not already have a peripheral IV line inserted
* Patients whose IV line cannot be transduced
* Patients with current or past vein thrombosis in the arm used to measure the pressure or with history of recurrent (\>1) pulmonary embolism
* Patients with active thrombophlebitis in the arm
* Patients who have experienced a major cardiovascular event (myocardial infarction, stroke, etc.) ≤2 months prior to the admission date
* Patients who have received an implanted cardiac resynchronization device (pacemaker or ICD) ≤3 months prior to admission date
* Patients enrolled in other cardiovascular research studies.
* Patients with a clinical condition that the investigator believes may not allow the patient to complete the study, at the discretion of the investigator. Examples of conditions that may apply include severe stenotic valvular disease, isolated right ventricle failure, precapillary pulmonary hypertension, hypertrophic obstructive cardiomyopathy, implanted left ventricular assist device, history of heart transplantation, clinical diagnosis of cardiogenic shock, any left-to-right shunt
* Patients with congenital heart disease or mechanical right heart valve(s)
* Planned heart surgery and/or coronary intervention during hospitalization
* Patients expected to receive heart transplant within 6 months of admission
* IV cannula smaller than 22G
* Patients who are pregnant and/or lactating
* Patients who are unable to provide informed consent
* Patients who are intubated

Where it's running

• Aurora St. Luke's Medical Center
  Milwaukee, Wisconsin, United States Recruiting

Study contacts

• Principal investigator: Khawaja Ammar, MD — Wake Forest University Health Sciences
• Study coordinator: Khawaja Ammar, MD
• Email: Khawaja.Ammar@aah.org
• Phone: (414) 649-6181

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Community-informed approaches to equitable heart failure care in primary care

  This study tests whether engaging patients, caregivers, community health workers, and care teams can help Mayo Clinic develop equity-focused, practical care strategies for adults with congestive heart failure who face social challenges.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT07730827

• Routine versus provisional distal perfusion catheter placement during mechanical circulatory support

  This study tests whether placing a distal perfusion catheter routinely or only provisionally improves limb outcomes in patients needing femoral artery support for mechanical circulatory support.

  Recruiting Samsung Medical Center · Changwon and 5 other locations · NCT07482865

• ADAPT palliative support for people living with heart failure

  This project will try weekly nurse- and social worker-led phone support (ADAPT) to see if it improves symptoms, mood, and quality of life for people living with heart failure in community clinics.

  Recruiting Indiana University · Indianapolis, Indiana · NCT07356843

• Using intra‑abdominal pressure and bedside ultrasound to guide decongestive treatment in heart failure

  This trial will test whether using bladder pressure (intra‑abdominal pressure) measurements together with bedside ultrasound to guide IV loop diuretics helps people hospitalized with acute heart failure get rid of excess fluid more effectively than usual care.

  Recruiting Phase 3 Instituto de Investigación Sanitaria Aragón · Zaragoza and 1 other locations · NCT07008365

• Pharmacy-led intervention to improve medication adherence after hospital discharge

  This study tests a pharmacy-led program to help low-income patients with multiple chronic conditions take their medications correctly after leaving the hospital.

  Recruiting University of Tennessee · Knoxville, Tennessee and 1 other locations · NCT06374277

• App to support post-hospital care for people with multiple chronic conditions

  This trial will test a smartphone/tablet app to help people aged 55+ with heart failure, diabetes, or chronic kidney disease manage their care after leaving the hospital.

  Recruiting Brigham and Women's Hospital · Boston, Massachusetts · NCT06051058

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.