Perceptions and Intentions Around a Change in CF Treatment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

PERCE-MUCO is a multicenter observational study using mixed methods to explore how adults with CF perceive a potential switch from ETI to VTD, including their expectations, satisfaction, and adherence. The project collects quantitative data via a purpose-built questionnaire plus routine CFQ-R 14+ and Morisky-8 measures, and qualitative insights from semi-structured interviews at a French CF center. The primary goal is to determine the proportion who would accept a switch and identify determinants of acceptance. Secondary aims examine quality of life relationships with switching intent, tolerability and adherence impacts, and the role of an advanced practice nurse during a potential transition. The study will describe barriers and facilitators to switching from patient and clinical perspectives.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of cystic fibrosis
* Currently treated with ETI for at least 3 months, OR previously treated with ETI but treatment discontinued for medical reasons

Exclusion Criteria:

* Patient objects to the use of their data for this project\\n•
* Currently receiving the new CFTR modulator VTD

Where it's running

• CRCM Giens
  Giens, France Recruiting
• CRCM Grenoble
  Grenoble, France Recruiting
• CRCM Montpellier
  Montpellier, France Recruiting
• CRCM Reims
  Reims, France Recruiting
• Fondation ILDYS
  Roscoff, France Recruiting
• CRCM Rouen
  Rouen, France Recruiting

Study contacts

• Study coordinator: Morgane Auffret, ResearchNurse
• Email: morgane.auffret@ildys.org
• Phone: 0298292523

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.