Clinical trial Recruiting at 1 site Interventional Ages 6 to 12

Autogenic Drainage vs. Mechanical Chest Percussion in Children with Cystic Fibrosis

Official title: Comparative Effects of Autogenic Drainage and Mechanical Percussion on Lung Function, Dyspnea and Quality of Life in Children With Cystic Fibrosis

Run by Riphah International University · NCT07729787 · Data updated 2026-11-12

In children aged 6-12 with cystic fibrosis, this study tests whether autogenic drainage helps lung function and comfort more than mechanical percussion.

More Cystic Fibrosis (CF) trials

Quick facts

Study typeInterventional
Ages6 Years to 12 Years
SexAll
Enrollment32 (estimated)
SponsorRiphah International University
Academic / other
Locations1 site (Multan Khurd, Punjab Province)
StatusRecruiting
StartedJune 14, 2026
Main results expectedNovember 30, 2026
Study endsNovember 30, 2026
Registry record updatedJuly 28, 2026
Trial IDNCT07729787 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Children aged 6-12 with a confirmed CF diagnosis who are clinically stable and able to participate in airway clearance therapy.

Probably not a fit

Children who do not respond to autogenic drainage or have contraindications to the therapies may not experience benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial compares two airway clearance techniques in CF patients: autogenic drainage and mechanical percussion. Participants are randomly assigned to one technique and receive supervised sessions five times a week for six weeks, with assessments of lung function, breathlessness, and quality of life. The study aims to see which method more effectively improves lung function and reduces dyspnea in pediatric CF patients. The trial is conducted at Nishter Hospital Multan, led by Riphah International University. Eligibility includes confirmed CF, age 6-12, and stable condition without recent pulmonary exacerbations.

Why it matters

Potential benefit: If autogenic drainage proves superior, children with CF might experience better breathing, fewer symptoms, and improved quality of life.

How similar studies have gone: Previous research has explored similar airway clearance methods, but direct comparisons in this age group are limited, making this study relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Confirmed diagnosis of cystic fibrosis (CF) through a sweat test or genetic testing.
* Age between 6 and 12 years.
* Clinically stable condition (no acute pulmonary exacerbation within the last 4 weeks).

Exclusion Criteria:

* History of thoracic surgery.
* Active hemoptysis.
* Severe physical or cognitive disabilities limiting participation in the intervention or assessments.

Where it's running

  • Nishter Hospital Multan
    Multan Khurd, Punjab Province, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.