Parastomal Hernia After Colorectal Cancer Surgery: Do Radiology Findings Match Quality of Life

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, longitudinal observational study of 135 patients in Region Skåne who had a permanent end colostomy for colorectal cancer. Participants will have routine CT scans at 1 and 3 years postoperatively, which will be reviewed to classify parastomal hernias by the European Hernia Society system and to track anatomical progression. At the same time, patients will answer validated stoma- and generic-quality of life questionnaires to see how imaging-detected hernias correspond to symptom burden and overall well-being. The study uses standard surveillance imaging and patient-reported outcomes to explore links between radiologic findings and QoL.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 years or older at the time of enrollment.
* Previous surgical resection for colorectal cancer resulting in a permanent end colostomy (abdominoperineal resection \[APR\] or Hartmann's procedure) performed within Region Skåne.
* Scheduled for routine oncological surveillance with thoracoabdominal computed tomography (CT) at 1 and/or 3 years postoperatively according to national clinical guidelines.
* Ability to provide written informed consent and completing Swedish self-administered questionnaires (Colostomy Impact Score and EQ-5D-5L).

Exclusion Criteria:

* Severe cognitive impairment or language barriers precluding the completion of the QoL questionnaires.

Where it's running

• Region Skåne, Skåne University Hospital
  Malmö, Skåne County, Sweden Recruiting

Study contacts

• Principal investigator: Marie-Louise Lydrup, MD, Assoc. Prof. — Region Skåne and the Department of Clinical Sciences, Faculty of Medicine, Lund University, Malmö, Sweden
• Study coordinator: Ali Al Mukhtar, MD
• Email: ali.almukhtar@skane.se
• Phone: +46707182726

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.