Risk factors for mesh infection after abdominal wall reconstruction

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, single-center observational cohort study at Minia University in Egypt. Consecutive adults undergoing abdominal wall reconstruction with mesh will be enrolled and followed for 12 months to identify independent risk factors for mesh-related infection within 90 days. Outcomes include infection timing, microbiology, need for mesh salvage or removal, and the occurrence of surgical site events, with an exploratory risk-stratification model to aid future risk prediction. No experimental interventions are applied; management follows standard unit practice. Enrollment spans 12 months, with complete follow-up for each participant lasting 12 months after surgery.</row>

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged ≥18 years.
* Undergoing elective or urgent abdominal wall reconstruction with implantation of synthetic, biosynthetic or biological mesh for a ventral, incisional, parastomal or complex abdominal wall defect.
* Able and willing to provide written informed consent and to attend scheduled follow-up.

Exclusion Criteria:

* Suture-only repair without mesh.
* Inguinal or femoral (groin) hernia repair.
* Active systemic sepsis or established intra-abdominal mesh infection at the time of index surgery.
* Mesh placed solely for a non-reconstructive indication (e.g. temporary abdominal closure or planned re-look without definitive reconstruction).
* Estimated life expectancy \< 12 months or inability to complete the minimum follow-up.
* Patient declines participation.

Where it's running

• Minia University Hospitals - Department of Surgery, Faculty of Medicine, Minia University
  Minya, Minya Governorate, Egypt Recruiting

Study contacts

• Principal investigator: Saleh K Saleh, MD — Minia University
• Study coordinator: Saleh K Saleh, MD
• Email: salehkhairy@mu.edu.eg
• Phone: 01201765401

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.