Using Gram Stain of Urine to Improve Outcomes After Kidney Stone Surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of using Gram staining of the first urine collected after renal puncture during percutaneous nephrolithotomy (PCNL) to predict systemic inflammatory responses. Patients will receive either an expanded empirical antibiotic regimen based on Gram stain results or a standard regimen adjusted according to symptoms and culture results. The goal is to assess whether this approach can help prevent complications and improve patient outcomes following surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* patients with an indication for percutaneous nephrolithotomy due to kidney stone disease.

Exclusion Criteria:

* under 18 years old,
* having an active urinary tract infection before surgery and positive urine cultures,
* Patients with bilateral kidney stones,
* DJ stent or nephrostomy placement,
* Solitary kidney stones,
* Bleeding disorders,
* impaired kidney function,
* a history of antibiotic use for any reason within 2 weeks before randomization were excluded from the study.

Where it's running

• Adıyaman University, Medicine of Faculty
  Adıyaman, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Bedreddin Kalyenci
• Email: bedreddin84@windowslive.com
• Phone: +905554859583

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Papillary vs non-papillary access during PCNL

  This trial tests whether non-papillary renal access is a safe and effective alternative to the standard papillary approach during percutaneous nephrolithotomy in adults with kidney stones.

  Recruiting Ain Shams University · Cairo · NCT07855354

• Flexible single-tract nephroscopy vs. multi-tract PCNL for complex kidney stones

  This randomized trial tests whether a flexible nephroscopy-assisted single-tract PCNL can match the stone-free rate of the standard multi-tract PCNL in people with complex unilateral kidney stones.

  Recruiting Al-Azhar University · Cairo · NCT07753733

• Inhaled anesthetics versus dexmedetomidine for maintaining general anesthesia

  This test compares dexmedetomidine plus remifentanil with desflurane plus remifentanil for adults over 39 having elective endoscopic urologic surgery to see which gives more stable anesthesia and faster recovery.

  Recruiting Bakirkoy Dr. Sadi Konuk Research and Training Hospital · Istanbul, Istanbul · NCT07363681

• Quadro Iliac Plane Block for Pain Control After Kidney Stone Surgery

  This study tests whether a regional block called QİPB can reduce pain after percutaneous nephrolithotomy in adults.

  Recruiting Cumhuriyet University · Sivas, Sivas · NCT07203859

• Prone versus supine positioning during percutaneous kidney stone removal (PCNL)

  This trial will test whether doing PCNL with the patient prone or supine gives more stable blood pressure and heart function during surgery for adults with large kidney stones.

  Recruiting Gaziosmanpasa Research and Education Hospital · Istanbul · NCT07138872

• Erector spinae block for pain control after kidney stone surgery

  This study tests if a special pain relief technique called the erector spinae block can help adults have less pain and use fewer opioids after kidney stone surgery.

  Recruiting University of Tennessee Medical Center · Knoxville, Tennessee · NCT05024344

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.