Pain and sleep problems in children who survived cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational case-control study compares childhood cancer survivors aged 6–12 who are up to 5 years post-treatment with age- and sex-matched healthy controls. It uses questionnaires, actigraphy, and sleep diaries to assess pain and sleep patterns over time. The goal is to understand how pain and sleep interact and to identify potential targets for prevention and intervention. The study is conducted at Vrije Universiteit Brussel with support from Research Foundation Flanders. The lead site is in Brussels, Belgium, and Dutch, French, and English language tools are used for participation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* CBC: 1) current age 6-12yo; 2) history of any cancer diagnosis; 3) ≤ 5y post- treatment completion; 4) ≥ 3 months since last cancer treatment (since pain and insomnia during treatment can be directly related to therapy and recover spontaneously); 5) fluent Dutch speaker and reader (age-dependent)
* Healthy controls (age- and sex-matched): 1) current age 6-12yo; 2) no history of cancer ; 3) fluent Dutch/French/English speaker and reader (age-dependent)
* Parents: 1) fluent Dutch/French/English speaker and reader

Exclusion Criteria:

* CBC: 1) receiving palliative therapy; 2) psychiatric disorder; 3) severe intellectual disability
* Healthy controls: 1) history of cancer; 2) psychiatric disorder; 3) severe intellectual disability

Where it's running

• Vrije Universiteit Brussel
  Brussels, Brussels Capital, Belgium Recruiting
• Vrije Universiteit Brussel
  Jette, Brussels Capital, Belgium Not yet recruiting

Study contacts

• Principal investigator: Emma Rheel, PhD — Vrije Universiteit Brussel
• Study coordinator: Emma Rheel, PhD
• Email: emma.rheel@vub.be
• Phone: +32496908353

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.