Evaluating fertility and ovarian function in female childhood cancer survivors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to assess the impact of low-intermediate dose alkylating agents and ovarian cryopreservation on ovarian function in female survivors of pediatric cancer. It will involve a cohort of female survivors aged 18 and older, analyzing their ovarian health and fertility outcomes. The study will also seek to identify new epigenetic markers that could predict the risk of premature ovarian insufficiency. Data will be collected from the Paediatrics Late Effects database and through fertility evaluations at specialized centers.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Child and adolescent female patients included in the Paediatrics Late Effects Project:
* diagnosed with cancer1 between 01/01/2004 and 31/12/2018
* \<17 years old at diagnosis
* treated at CHU Liège site Citadelle or CHC, Cliniques Universitaires Saint-Luc and HUDERF
* alive
* ≥ 18 years-old at time of recruitment.

Exclusion Criteria:

* Cancer diagnosis for controls

Where it's running

• Hopital de la Citadelle
  Liège, Wallonia, Belgium Recruiting
• Cliniques Universitaires Saint-Luc
  Brussels, Belgium Not yet recruiting
• Huderf
  Brussels, Belgium Not yet recruiting

Study contacts

• Study coordinator: Bianca David, MD
• Email: bianca.andreea.david@citadelle.be
• Phone: 32 4 321 87 39

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.