Optimizing pain management for a specific type of lung surgery
Optimization of Perioperative Analgesia Protocol for Uniportal Video-assisted Thoracoscopic Surgery: a Randomized Controlled Trial
This study is testing which pain relief method works best for patients recovering from a specific type of lung surgery to help them feel better and heal faster.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 102 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | China-Japan Friendship Hospital Academic / other |
| Locations | 1 site (Beijing, Beijing) |
| Trial ID | NCT06016777 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to enhance postoperative pain management for patients undergoing uniportal video-assisted thoracoscopic surgery (uVATS). It is a single-blind randomized controlled study that will compare the effectiveness of three different analgesic techniques: thoracic paravertebral block, erector spinae block, and patient-controlled intravenous analgesia with sufentanil. A total of 102 patients will be enrolled and followed up at various intervals post-surgery to assess pain levels, ambulation time, and hospital stay duration. The study seeks to determine the optimal analgesic approach to improve recovery outcomes for these patients.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with early-stage lung cancer or those requiring intrathoracic tissue biopsy, who are suitable for elective uVATS.
Not a fit: Patients with severe comorbidities, chronic pain, or contraindications to the analgesic methods being tested may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly reduce postoperative pain and improve recovery times for patients undergoing lung surgery.
How similar studies have performed: Previous studies have shown promising results with similar analgesic techniques in thoracic surgery, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. ≥18 years 2. ASA I-IIa 3. Early stage lung cancer or intrathoracic tissue biopsy, suitable for elective uVATSb 4. Informed consent obtained Exclusion Criteria: 1. ASA≥III 2. History of intrathoracic or chest wall surgery 3. Chronic pain 4. Pre-operative analgesic medication use 5. NSAIDsc contraindications: aspirin asthma, allergic to NSAIDs, peptic ulcer, liver and kidney insufficiency, high risk of thrombotic events 6. Active autoimmune disease 7. Allergic to local anesthetics 8. Severe coagulation dysfunction, contraindicated for nerve block 9. Soft tissue infections of the chest wall
Where this trial is running
Beijing, Beijing
- China-Japan Friendship Hospital — Beijing, Beijing, China (Recruiting)
Study contacts
- Study coordinator: Li Fang WANG, Doctor
- Email: lilythewolf@sina.com
- Phone: +8615011393879
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.