Observing osteoarticular infections in intensive care patients
OSTEOARTICULAR SEPSIS ON EQUIPMENT in Intensive Care and Continuing Care Units in France
Assistance Publique - Hôpitaux de Paris · NCT06627842
This study looks at patients in intensive care with joint infections, especially those with knee and hip implants, to understand their treatment, outcomes, and what factors might affect their survival over two years.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 150 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Assistance Publique - Hôpitaux de Paris (other) |
| Locations | 1 site (Paris, France) |
| Trial ID | NCT06627842 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on patients admitted to critical care with osteoarticular infections, particularly those involving knee and hip prostheses. It aims to describe patient profiles, care trajectories, and prognosis during their hospital stay, while also comparing outcomes among different patient groups. The study will assess independent risk factors for 2-year mortality and analyze the microbiological and resistance profiles of severe infections. Data will be collected from patient records across French public and private hospitals.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who have been admitted to intensive care with a diagnosis of osteoarticular infection.
Not a fit: Patients under legal protection, pregnant or breastfeeding, or deprived of liberty may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of osteoarticular infections and improve patient management strategies in critical care settings.
How similar studies have performed: While this study is observational and descriptive, similar studies have provided valuable insights into critical care infections, suggesting potential for meaningful findings.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient at least 18 years old. * Hospitalization in critical care (intensive care unit or continuing care unit) between 2018 and 2022 of at least 48 hours, with prosthetic joint infection (hip, knee or shoulder prosthesis infection) as the main or associated diagnosis. Exclusion Criteria: * Infection on osteosynthesis material * Infection on spinal equipment * Patient with several infected prostheses * Recurrence of infection on prosthesis with the same microorganism * Patient opposing data collection * Patient under legal protection. * Pregnant or breast-feeding patient. * Patient deprived of liberty.
Where this trial is running
Paris, France
- Hôpital Lariboisière — Paris, France, France (RECRUITING)
Study contacts
- Study coordinator: Benjamin SOYER, MD, Msc
- Email: benjamin.soyer@aphp.fr
- Phone: +33 1 49 95 85 15
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Osteoarticular Infection, Intensive Care Patients, Prosthetic Joint Infection, Osteoarticular sepsis, sepsis, osteoarticular prothetis, intensive care, critical care