Observational study on the effectiveness of biological treatments for inflammatory joint diseases

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study, known as NOR-DMARD, aims to evaluate the effectiveness and long-term safety of biological disease modifying anti-rheumatic drugs (DMARDs) in treating inflammatory joint diseases such as rheumatoid arthritis and psoriatic arthritis. It involves structured follow-up visits at baseline and at regular intervals to assess disease activity, health-related quality of life, and joint damage. The study also collects blood samples for biobanking and systematically records serious adverse events, while exploring predictors of treatment efficacy and cost-effectiveness. The data gathered will help improve treatment strategies and patient outcomes in clinical practice.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age \>18 years
* Diagnosis of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, spondyloarthritis, adult juvenile idiopathic arthritis, undifferentiated arthritis, or any other inflammatory arthritis
* Clinical indication to start a new treatment with a biological disease modifying anti-rheumatic drug or a kinase inhibitor

Exclusion Criteria:

* Unwillingness or unability to give written informed consent
* Psychiatric or mental disorders, alcohol abuse or other abuse of substances, language barriers or other factors which makes adherence to the study protocol impossible
* Participation in blinded RCTs or other studies incompatible with the NOR-DMARD study protocol

Where it's running

• Lillehammer Hospital for Rheumatic Diseases
  Lillehammer, Oppland, Norway Recruiting
• Førde Hospital
  Førde, Sogn Og Fjordane, Norway Recruiting
• University Hospital of Northern Norway
  Tromsø, Troms, Norway Recruiting
• Diakonhjemmet Hospital
  Oslo, Norway Recruiting
• Vestre Viken HF Drammen Hospital
  Drammen, Buskerud, Norway Completed
• St. Olavs Hospital
  Trondheim, Sør-Trøndelag, Norway Completed

Study contacts

• Principal investigator: Tore K Kvien, MD, PhD — Diakonhjemmet Hospital
• Study coordinator: Eirik K Kristianslund, MD, PhD
• Email: eirik.kristianslund@gmail.com

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.