Observational study on spastic paraplegia
A Registered Cohort Study on Spastic Paraplegia
This study is trying to learn more about how hereditary spastic paraplegia affects people over time so that doctors can better manage the condition.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Sex | All |
| Sponsor | First Affiliated Hospital of Fujian Medical University Academic / other |
| Locations | 1 site (Fuzhou) |
| Trial ID | NCT04006418 on ClinicalTrials.gov |
What this trial studies
This study aims to explore the clinical spectrum and natural progression of Hereditary Spastic Paraplegias (HSP) and related disorders through a multicenter observational approach. It will assess various clinical, genetic, and epigenetic features of patients diagnosed with spastic paraplegia. The goal is to optimize clinical management by gathering comprehensive data on the condition's progression and characteristics.
Who should consider this trial
Good fit: Ideal candidates include patients with a clinical diagnosis of spastic paraplegia and unrelated healthy controls.
Not a fit: Patients who decline to participate or have serious interferences with participation may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding and management of spastic paraplegia, leading to improved patient care.
How similar studies have performed: While this study focuses on a specific condition, similar observational studies have shown success in understanding the natural history of other neurological disorders.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with the clinical diagnosis of spastic paraplegia * Clinical diagnosis of patients with spastic paraplegia * Unrelated healthy controls Exclusion Criteria: * Decline to participate. * There are serious interferences with individual participation and adherence to the research protocol, including but not limited to neurological, psychological, and/or medical conditions.
Where this trial is running
Fuzhou
- First Affiliated Hospital Fujian Medical University — Fuzhou, China (Recruiting)
Study contacts
- Study coordinator: Yi Lin, MD,PhD
- Email: wanjinchen75@fjmu.edu.cn
- Phone: +13615039153
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.