Registry for hereditary cardiovascular diseases in Brazil

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to create a registry of Brazilian patients diagnosed with hereditary cardiovascular diseases by collecting both clinical and genomic data. Participants will undergo whole genome sequencing to identify common genetic alterations associated with these conditions. The study will involve interviews during routine medical visits to gather necessary information and consent. The primary focus is to understand the frequency of genetic mutations in the Brazilian population affected by various types of cardiomyopathy and related disorders.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Clinical diagnosis of a hereditary cardiovascular disease according to current clinical guidelines
* Agree to receive genetic counseling
* Sign informed consent form
* Provide the information required in the case report form

Exclusion Criteria:

* Signature absent from informed consent form
* Inadequate buccal swab (sample may be collected twice)

Where it's running

• Centro de Pesquisa Silvestre Santé
  Rio Branco, Acre, Brazil Recruiting
• Centro de Pesquisas Clínicas Dr. Marco Mota
  Maceió, Alagoas, Brazil Recruiting
• Hospital Universitário da Unifap
  Macapá, Amapá, Brazil Recruiting
• Hospital de Messejana Dr. Carlos Alberto Studart Gomes
  Fortaleza, Ceará, Brazil Recruiting
• Hospital Evangélico de Vila Velha
  Vila Velha, Espírito Santo, Brazil Recruiting
• Hospital Universitário Professor Edgard Santos
  Salvador, Estado de Bahia, Brazil Recruiting

Study contacts

• Study coordinator: Adriana Bastos Carvalho, MD PhD
• Email: carvalhoab@biof.ufrj.br
• Phone: +552130372105

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Long-term outcomes for patients with cardiac arrhythmias

  This study looks at how well treatments for heart rhythm problems work over time and what factors might affect their success for patients with conditions like atrial fibrillation and ventricular tachycardia.

  Recruiting Universitätsklinikum Hamburg-Eppendorf · Hamburg · NCT05521451

• Pregnancy-Related Aortic Dissection in China

  This study looks at cases of aortic dissection that occur during pregnancy or shortly after, to understand outcomes for mothers and babies.

  Recruiting at 4 sites DeltaHealth Hospital · Shanghai · Shanghai, Shanghai Municipality and 3 other locations · NCT07672210

• Comparing direct and indirect methods for screening family members at risk for genetic conditions

  This study is testing two ways to reach out to family members at risk for Long QT Syndrome and Familial Hypercholesterolemia to see which method helps them get screened better, while also offering free genetic testing and counseling.

  Recruiting University of Maryland, Baltimore · Lancaster, Pennsylvania · NCT05348564

• Using cheek (buccal) cells to detect cell-junction protein changes in inherited arrhythmias

  This project will test whether a painless cheek-swab can reveal the same heart cell-junction protein changes in people with inherited arrhythmias such as arrhythmogenic cardiomyopathy, Brugada syndrome, and other channelopathies.

  Recruiting St. George's Hospital, London · London · NCT04257994

• Monitoring fetal heart activity in high-risk pregnancies to prevent stillbirth

  This study is testing a new way to monitor fetal heart activity in high-risk pregnancies to see if it can help prevent stillbirth.

  Recruiting at 2 sites Medical College of Wisconsin · Madison, Wisconsin and 1 other locations · NCT03775954

• Registry and biobank for arrhythmogenic ventricular cardiomyopathy

  This study is trying to gather information and samples from people with arrhythmogenic ventricular cardiomyopathy and their families to better understand the genetic causes of the condition and improve early diagnosis for those at risk.

  Recruiting at 2 sites Mayo Clinic · Rochester, Minnesota and 1 other locations · NCT03049254

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.