Observational study on Ewing's sarcoma of the bone

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to collect comprehensive data on the demographic, clinical, surgical, pathological, and molecular characteristics of patients diagnosed with skeletal Ewing's sarcoma. The study will gather information on treatment approaches, including chemotherapy, surgery, and radiotherapy, to better understand the disease's biological behavior and improve treatment strategies. By analyzing data from patients with localized and metastatic disease, the study seeks to enhance knowledge that could inform future clinical trials and treatment protocols.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Diagnosis of Ewing's sarcoma of the bone
2. Diagnosis of Ewing-like sarcoma (round cell sarcoma with fusion of the EWSR1 gene with others not of the ETS family, sarcoma with CIC rearrangement or sarcoma with BCOR rearrangement)
3. Diagnosis of extraosseous Ewing's sarcoma for patients
4. Age at diagnosis \<50 years
5. Assessment of the extent of the disease at onset in accordance with the European Society of Medical Oncology guidelines
6. Patients or parents oe guardians of minors who have given their written informed consent to participate in the study

Exclusion Criteria:

1\. Presence of comorbid factors who can compromise the compliance of the treatment plan or the evaluation of the outcomes, including but not limited to organ pathologies that contraindicate the use of chemotherapy and psychological or social conditions that do not allow for adequate compliance treatment or adequate follow-up

Where it's running

• Istituto Clinico Humanitas
  Rozzano, Mi, Italy Recruiting
• Centro di Riferimento Oncologico - Unit of Medical Oncology
  Aviano, Pordenone, Italy Recruiting
• I.R.C.C. - Unit of Medical Oncology
  Candiolo, Torino, Italy Recruiting
• Azienda ospedaliero universitaria consorziale policlinico - bari
  Bari, Italy Recruiting
• A.O. Universitaria Policlinico S. Orsola Malpighi di Bologna
  Bologna, Italy Recruiting
• Istituto ortopedico Rizzoli
  Bologna, Italy Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.