Observational study on breast sarcoma characteristics and outcomes
Breast Sarcomas: A Retrospective Analysis of Clinical Features and Outcomes
Italian Sarcoma Group · NCT04749446
This study looks at the characteristics and treatment outcomes of patients with breast sarcoma to help improve care for this rare type of tumor.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 19 Years and up |
| Sex | All |
| Sponsor | Italian Sarcoma Group (network) |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 14 sites (Bologna, BO and 13 other locations) |
| Trial ID | NCT04749446 on ClinicalTrials.gov |
What this trial studies
This multi-institutional retrospective study aims to identify key clinical features and treatment strategies for patients with breast sarcoma, a rare type of soft tissue tumor. Data will be collected from patients referred to participating institutions between January 2000 and June 2020, focusing on their clinical history and outcomes. The study seeks to address the lack of specific prospective trials in this area by analyzing existing medical data to inform better management and treatment principles for breast sarcomas.
Who should consider this trial
Good fit: Ideal candidates include adults over 18 years diagnosed with primary or secondary breast sarcoma who have available medical data.
Not a fit: Patients with sarcoma metastases to the breast or those with chest wall sarcomas not arising in the mammary gland will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the understanding and management of breast sarcoma, leading to better patient outcomes.
How similar studies have performed: While there is a lack of specific prospective trials for breast sarcoma, similar retrospective studies in other sarcoma types have provided valuable insights, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * \>18 years at diagnosis * primary or secondary breast sarcoma * availability of medical data needed for the study (histopathological data, surgery, chemotherapy, including preceding chemotherapeutic regimens for secondary breast sarcomas, radiation therapy) Exclusion Criteria: * sarcoma metastases to the breast * chest wall sarcomas not arising in the mammary gland * cutaneous sarcomas
Where this trial is running
Bologna, BO and 13 other locations
- Azienda Ospedaliera S. Orsola-Malpighi — Bologna, BO, Italy (NOT_YET_RECRUITING)
- Istituto Europeo di Oncologia — Milan, MI, Italy (NOT_YET_RECRUITING)
- Istituto Clinico Humanitas — Rozzano, MI, Italy (NOT_YET_RECRUITING)
- Azienda Ospedaliera Universitaria Paolo Giaccone — Palermo, PA, Italy (NOT_YET_RECRUITING)
- Centro di Riferimento Oncologico - Unit of Medical Oncology — Aviano, Pordenone, Italy (NOT_YET_RECRUITING)
- Ospedale Misericordia e Dolce — Prato, PO, Italy (NOT_YET_RECRUITING)
- Policlinico Universitario Campus Biomedico — Roma, RM, Italy (NOT_YET_RECRUITING)
- Fondazione del Piemonte per l'Oncologia IRCC Candiolo — Candiolo, Torino, Italy (RECRUITING)
- Ospedale Umberto I — Turin, TO, Italy (NOT_YET_RECRUITING)
- A.O Ospedali Riuniti Marche Nord — Ancona, Italy (NOT_YET_RECRUITING)
- Azienda Ospedaliera Universitaria Careggi — Florence, Italy (NOT_YET_RECRUITING)
- Fondazione IRCCS INT Milano — Milan, Italy (NOT_YET_RECRUITING)
- Istituto Nazionale Tumori Regina Elena - Unit of Medical Oncology I — Roma, Italy (NOT_YET_RECRUITING)
- ASL Città di Torino (Dipartimento di Oncologia) — Torino, Italy (NOT_YET_RECRUITING)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Breast Sarcoma