Observational study of localized osteosarcoma characteristics and treatments

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to collect demographic, clinical, surgical, pathological, and molecular data from patients diagnosed with localized osteosarcoma. It focuses on individuals treated according to the AIEOP/Italian Sarcoma Group OS 2021 guidelines, which include a combination of chemotherapy and surgical intervention. The study will gather information on treatment outcomes and characteristics to enhance understanding of this rare disease. By documenting these factors, the study seeks to improve future treatment protocols for localized osteosarcoma.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of high grade OS of the extremities
* Age at diagnosis ≤ 40 years at the time of diagnosis
* Localized disease (skip metastases are allowed)
* Adequate organ function according the AIEOP/ISG OS 2021 recommendation
* Patients or parents oe guardians of minors who have given their written informed consent to participate in the study

Exclusion Criteria:

* Presence of metastases
* Diagnosis of periosteal OS, of parosteal OS or secondary OS
* Any medical condition which can not allowed the use of the treatments recommended by AIEOP/ISG OS 2021

Where it's running

• Centro di Riferimento Oncologico - Unit of Medical Oncology
  Aviano, Pordenone, Italy Recruiting
• Sandra Aliberti
  Candiolo, Torino, Italy Recruiting
• IRCCS materno infantile Burlo Garofolo
  Trieste, T, Italy Recruiting
• Azienda Ospedaliero Universitaria Consorziale Policlinico - Bari
  Bari, Italy Recruiting
• IRCCS Istituto ortopedico Rizzoli
  Bologna, Italy Recruiting
• A.O. Universitaria Policlinico S. Orsola Malpighi di Bologna
  Bologna, Italy Recruiting

Study contacts

• Study coordinator: Franca Fagioli, MD/Prof
• Email: franca.fagioli@unito.it
• Phone: 0039-0113135

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.