Observational study on advanced chronic liver diseases in Vienna

VICIS - Vienna Cirrhosis Study

Observational Medical University of Vienna · NCT03267615

This study looks at patients with advanced chronic liver diseases in Vienna to see how their condition affects blood pressure in the liver and to collect samples for future research.

Quick facts

Study typeObservational
Enrollment10000 (estimated)
Ages18 Years to 100 Years
SexAll
SponsorMedical University of Vienna Academic / other
Locations1 site (Vienna)
Trial IDNCT03267615 on ClinicalTrials.gov

What this trial studies

The VICIS study involves patients with advanced chronic liver diseases treated at the Vienna General Hospital. Participants will undergo regular follow-ups and clinical visits, during which clinical and laboratory parameters will be recorded. The study aims to assess the degree of portal hypertension and other related conditions through various diagnostic methods, including HVPG measurement and liver stiffness assessment. Additionally, a biobank will be established to collect biological samples from participants for further research.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 to 100 with advanced chronic liver disease as indicated by specific clinical criteria.

Not a fit: Patients who do not have advanced chronic liver disease or those who withdraw consent will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the understanding and management of advanced chronic liver diseases, potentially leading to improved patient outcomes.

How similar studies have performed: Other studies focusing on advanced chronic liver diseases have shown promise in improving patient management, making this approach relevant and potentially impactful.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age \>18 years and \<100 years
* Diagnosis of advanced chronic liver disease (by liver stiffness ≥10kPa, HVPG\>5mmHg or Histology F3/F4)
* Written informed consent

Exclusion Criteria:

* Withdrawal of written informed consent

Where this trial is running

Vienna

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Liver CirrhosisPortal HypertensionAscitesVariceal HemorrhageHepatic Encephalopathy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.