Observational study on advanced chronic liver diseases in Vienna
Official title: VICIS - Vienna Cirrhosis Study
Run by Medical University of Vienna · NCT03267615 · Data updated 2026-11-12
This study looks at patients with advanced chronic liver diseases in Vienna to see how their condition affects blood pressure in the liver and to collect samples for future research.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 10000 (estimated) |
| Sponsor | Medical University of Vienna Academic / other |
| Locations | 1 site (Vienna) |
| Status | Recruiting |
| Started | February 1, 2017 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2027 |
| Registry record updated | September 25, 2025 |
| Trial ID | NCT03267615 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 to 100 with advanced chronic liver disease as indicated by specific clinical criteria.
✕Probably not a fit
Patients who do not have advanced chronic liver disease or those who withdraw consent will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The VICIS study involves patients with advanced chronic liver diseases treated at the Vienna General Hospital. Participants will undergo regular follow-ups and clinical visits, during which clinical and laboratory parameters will be recorded. The study aims to assess the degree of portal hypertension and other related conditions through various diagnostic methods, including HVPG measurement and liver stiffness assessment. Additionally, a biobank will be established to collect biological samples from participants for further research.
Why it matters
Potential benefit: If successful, this study could enhance the understanding and management of advanced chronic liver diseases, potentially leading to improved patient outcomes.
How similar studies have gone: Other studies focusing on advanced chronic liver diseases have shown promise in improving patient management, making this approach relevant and potentially impactful.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \>18 years and \<100 years * Diagnosis of advanced chronic liver disease (by liver stiffness ≥10kPa, HVPG\>5mmHg or Histology F3/F4) * Written informed consent Exclusion Criteria: * Withdrawal of written informed consent
Where it's running
-
Medical University of Vienna
Vienna, Austria Recruiting
Study contacts
- Principal investigator: Thomas Reiberger, M.D. — Medical University of Vienna
- Study coordinator: Thomas Reiberger, M.D.
- Email: thomas.reiberger@meduniwien.ac.at
- Phone: +43140400
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.