Observational study for patients with gastric MALT lymphoma
Establishment of a Cohort for Investigating the Pathophysiology of Gastric MALT Lymphoma
This study is collecting health information and tissue samples from people with gastric MALT lymphoma to help understand the disease better and support future treatments.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Seoul National University Hospital Academic / other |
| Locations | 3 sites (Ansan-si, Gyeonggi-do and 2 other locations) |
| Trial ID | NCT06454149 on ClinicalTrials.gov |
What this trial studies
This observational study aims to gather clinical data and create a tissue repository for patients diagnosed with gastric MALT lymphoma, as well as for control participants. Patients will provide clinical information and various tissue samples, including saliva, gastric mucosa, and feces. The study will help in understanding the disease better and may contribute to future research and treatment strategies.
Who should consider this trial
Good fit: Ideal candidates include individuals newly diagnosed with gastric MALT lymphoma and those undergoing upper endoscopy for related conditions.
Not a fit: Patients with a history of gastric or other malignancies or those with uncontrolled chronic illnesses may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of gastric MALT lymphoma and improve future treatment options for patients.
How similar studies have performed: While this approach is observational and may not have direct precedents, similar studies in lymphoma research have shown promise in understanding disease mechanisms.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: \[MALT lymphoma group\] * Newly diagnosed as gastric MALT lymphoma \[Control group\] * Patients who underwent 1. diagnosed upper endoscopy for dyspepsia and had chronic gastritis, 2. therapeutic upper endoscopy for gastric hyperplastic polyps, or 3. screening upper endoscopy without any symptoms. Exclusion Criteria: * History of gastric or other malignancy * Use of antibiotics or probiotics within 4 weeks * Uncontrolled chronic illnesses
Where this trial is running
Ansan-si, Gyeonggi-do and 2 other locations
- Korea University Ansan Hospital — Ansan-si, Gyeonggi-do, South Korea (Not_yet_recruiting)
- Cheol Min Shin — Seongnam-si, Gyeonggi-do, South Korea (Recruiting)
- Kangbuk Samsung Hospital — Seoul, South Korea (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.