Non‑trauma PTSD treatment for veterans and service members with mild or moderate TBI
Non-Trauma Intervention to Treat Posttraumatic Stress Disorder (PTSD) for Veterans and Service Members Suffering From a Traumatic Brain Injury (TBI)
This pilot will test a non‑trauma psychotherapy program to help veterans and service members with mild or moderate traumatic brain injury who have PTSD.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | The University of Texas Health Science Center at San Antonio Academic / other |
| Locations | 1 site (Fort Hood, Texas) |
| Trial ID | NCT07351305 on ClinicalTrials.gov |
What this trial studies
This pilot tests a tailored non‑trauma intervention called T3 PTSD that provides individual psychotherapy sessions for veterans and active duty service members with mild or moderate TBI and comorbid PTSD. Twenty participants will be enrolled at Carl R Darnall Army Medical Center (Fort Hood, Texas) and receive the T3 PTSD intervention while standardized measures such as the Clinician‑Administered PTSD Scale (CAPS‑5) are used to track symptoms. The primary goals are to establish feasibility and acceptability of the approach, with secondary collection of symptom, functional, and safety outcomes before and after treatment. Eligible participants must be English‑speaking adults with TBI identified by the Ohio State University Brain Injury Identification Method and meet CAPS‑5 criteria for PTSD.
Who should consider this trial
Good fit: Ideal candidates are English‑speaking veterans or active duty service members aged 18 or older with mild or moderate TBI and a CAPS‑5 diagnosis of PTSD who are not currently in another PTSD behavioral therapy.
Not a fit: Patients actively engaged in another behavioral PTSD treatment, those with psychiatric problems requiring immediate care, or non‑English speakers are unlikely to benefit from participation.
Why it matters
Potential benefit: If successful, the treatment could reduce PTSD symptoms in veterans and service members with TBI using a non‑trauma approach that may be easier for patients with cognitive or memory difficulties to tolerate.
How similar studies have performed: Non‑trauma and skills‑based PTSD treatments have shown promise in some groups, but tailored interventions specifically for people with comorbid TBI are relatively novel and supported mainly by early‑stage studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Ability of participant to understand and the willingness to sign a written informed consent document based on interviewer assessment and clinical judgement. 2. Any veteran or active duty service member (age 18 or above) diagnosed with mild or moderate TBI as determined by the Ohio State University Brain Injury Identification Method 3. Participant meets diagnostic criteria for PTSD based on Clinician-Administered PTSD Scale (CAPS-5) interview as described by the National Center for PTSD which includes at least one Criterion B symptom, one Criterion C symptom, two Criterion D symptoms, and two Criterion E symptoms as well as meeting Criterions F and G. 4. Ability to read, write, and speak English based on interviewer assessment and clinical judgement. Exclusion Criteria: 1. Participant is actively engaged in a behavioral intervention primarily targeting PTSD. 2. Participant has a psychiatric problem that warrants immediate treatment as indicated in the electronic health record, flagged during testing, or confirmed by a clinician through screening or review of clinical notes. 3. Participant demonstrates significant cognitive impairment that could impact treatment adherence/benefit based on interviewer assessment and clinical judgement.
Where this trial is running
Fort Hood, Texas
- Carl R Darnall Army Medical Center — Fort Hood, Texas, United States (Recruiting)
Study contacts
- Principal investigator: Cindy McGeary, PhD — The University of Texas Health Science Center at San Antonio
- Study coordinator: Cindy McGeary, PhD
- Email: mcgearyc@uthscsa.edu
- Phone: 210-567-5497
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.