Clinical trial Recruiting at 1 site Observational Ages 18 and up

Neuromuscular Profiles After ACL Reconstruction

Official title: Exploratory Study of Neuromuscular Profiles After Anterior Cruciate Ligament Reconstruction in Clinical Conditions: Combined Analysis of Isokinetic Strength and Surface Electromyography

Run by Hopitaux de Saint-Maurice · NCT07792863 · Data updated 2026-11-12

This study tests how quadriceps and hamstring strength and muscle activation patterns look 4–12 months after ACL reconstruction to see if distinct neuromuscular profiles emerge.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment30 (estimated)
SponsorHopitaux de Saint-Maurice
Academic / other
Locations1 site (Saint-Maurice, Demande)
StatusRecruiting
StartedAugust 21, 2026
Main results expectedDecember 1, 2026
Study endsDecember 31, 2026
Registry record updatedSeptember 29, 2026
Trial IDNCT07792863 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18 years or older who are 4 to 12 months post-ACL reconstruction and can participate in isokinetic testing.

Probably not a fit

Patients with conditions or circumstances preventing safe testing or participation may not benefit from the study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a monocentric, observational cross-sectional study of adults 18+ who are 4 to 12 months post-ACL reconstruction. It combines routine strength testing with isokinetic measures, a single-leg hop test, and surface EMG of key thigh muscles to describe neuromuscular patterns under both analytical and functional conditions. Patient-reported questionnaires on knee self-efficacy, fear of movement, symptoms, and function are collected to contextualize the neuromuscular data. The goal is to map joint distributions of strength and activation and explore associations with functional performance and self-reported outcomes. Findings may help identify distinct profiles that could inform rehabilitation approaches.

Why it matters

Potential benefit: If successful, the study could help tailor rehabilitation by identifying neuromuscular profiles linked to better function.

How similar studies have gone: Previous work has shown persistent strength deficits after ACL reconstruction, but few studies combine isokinetic and EMG data across agonist and antagonist muscles in the same cohort.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Anterior cruciate ligament (ACL) reconstruction.
* Postoperative period between 4 and 12 months.
* Age 18 years or older.
* Affiliation with or beneficiary of a social security scheme.
* Ability to understand the study information and to express non-opposition to participation.

Exclusion Criteria:

* Persons under guardianship, curatorship, or another legal protection measure.
* Any condition preventing safe performance of isokinetic testing, including significant pain, significant joint effusion, substantial limitation of joint range of motion, clinical knee instability, or an ongoing postoperative complication.
* Opposition to participation in the study.

Where it's running

  • Hôpitaux Paris Est Val-de-Marne - Service de rééducation orthopédique et traumatologie
    Saint-Maurice, Demande, France
    Recruiting

Study contacts

  • Principal investigator: Sylvain BS BELOT, md — Hopitaux Paris Est Val-de-Marne
  • Study coordinator: Sylvain SB BELOT, MD
  • Email: sylvain.belot@hpevm.fr
  • Phone: +33143966383

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.