Muscle loss in pregnant women with gestational diabetes.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational project enrolls pregnant women at risk for gestational diabetes and performs sarcopenia tests (muscle mass, strength, and physical performance), an oral glucose tolerance test (OGTT), and the Montreal Cognitive Assessment (MoCA). Muscle measures will be compared with glucose tolerance results, pregnancy outcomes, and cognitive screening scores. Women with twin pregnancies, known diabetes, neurological/psychiatric disease, or other conditions affecting muscle are excluded. Recruitment and testing occur at centers in Vienna, Padova, and Pisa to determine whether sarcopenia occurs in gestational diabetes and whether it links to adverse maternal, neonatal, or cognitive outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

At least one among the following conditions:

* Age equal to or higher than 35 years;
* Body mass index (BMI) equal to or higher than 25 kg/m\^2;
* Glycemia between 5.6 and 6.9 mmol/L before or at the beginning of pregnancy;
* Fetal macrosomia in previous pregnancy;
* GDM in previous pregnancy;
* First-degree family history of diabetes.

Exclusion Criteria:

* Unmatching of at least one among the inclusion criteria;
* Twin pregnancy;
* Presence of any already known disease/disorder possibly affecting muscle mass or function;
* Neurological or psychiatric diseases;
* Already known diabetes (e.g., type 1 or type 2 diabetes).

Where it's running

• Department of Obstetrics and Gynaecology, Division of Obstetrics and Feto-Maternal Medicine, Medical University of Vienna, Vienna
  Vienna, Austria Recruiting
• Department of Clinical and Experimental Medicine, University of Pisa
  Pisa, Pi, Italy Recruiting
• Institute of Neuroscience, National Research Council
  Padova, Pd, Italy Active not recruiting

Study contacts

• Study coordinator: Andrea Tura
• Email: andrea.tura@cnr.it
• Phone: +390498295786

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Bone marrow mesenchymal stem cell injection for sarcopenia

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  Recruiting Phase 1/2 GuangZhou Cellgenes Biotechnology Co., Ltd. · Guangzhou · NCT07865676

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.