Multicomponent exercise to improve function, cognition, and reduce falls in nursing home residents

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a randomized, controlled 12-week trial comparing a multicomponent exercise program (resistance/power, balance, and aerobic training) with an active control stretching and relaxation program in older adults living in nursing homes. Participants who can ambulate and perform chair stands and can follow testing procedures will be randomized to one of the two interventions. Primary outcomes include changes in physical function, cognitive performance, and fall rates, with secondary analyses examining whether effects persist after the intervention period. The trial is conducted by the University of Porto and targets institutionalized older adults with frailty and/or cognitive impairment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Ability to ambulate (with or without assistance);
* Ability to perform chair stands (with or without assistance);
* Ability to understand and properly follow testing procedures.

Exclusion Criteria:

* Any contraindication that precludes exercise performance or testing procedures, including terminal illness, uncontrolled disease, or other unstable medical conditions;
* Short Physical Performance Battery (SPPB) score \< 3 points;
* Participation in any exercise intervention within the past 3 months;
* Simultaneous participation in another clinical trial during the study;
* Planned transfer to another nursing home facility, to home, or to hospitalization during the intervention.

Where it's running

• Faculty of Sports, University of Porto
  Porto, Portugal Recruiting

Study contacts

• Principal investigator: Maria Joana Carvalho, PhD — Universidade do Porto
• Study coordinator: Maria Joana Carvalho, PhD
• Email: Jcarvalho@fade.up.pt
• Phone: +351 220425316

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• How environment and biology together predict health, aging, and death

  Researchers are following adults to see how living conditions and biology together relate to aging and life expectancy, by linking personal health data with environmental and social information over time.

  Recruiting Longevity Metrics, Inc. · Boulder, Colorado · NCT07646782

• 100-Year Human Aging and Longevity Tracking Program

  This project will follow adults over their lifetimes to see if repeated health tests can predict lifespan, causes of death, serious disease, and loss of function.

  Recruiting Longevity Metrics, Inc. · Boulder, Colorado · NCT07563777

• Diabetes, Dementia, and Oxidative Stress: A look at Nox2-related markers

  This study tests whether oxidative stress linked to Nox2 is related to dementia risk in adults with type 2 diabetes.

  Recruiting Neuromed IRCCS · Pozzilli · NCT07928453

• Postprandial drop and frailty in older adults having planned noncardiac surgery

  This study tests whether a drop in blood pressure after meals and frailty predict low blood pressure after anesthesia starts in adults 65 and older undergoing planned noncardiac surgery.

  Recruiting Konya City Hospital · Konya, Konya · NCT07914920

• China HEAD: a large community study on healthy aging and dementia

  This study tests whether collecting health, imaging, and biospecimen data from adults in China can help predict who will develop Alzheimer’s disease and related dementias.

  Recruiting at 30 sites Fudan University · Beijing and 29 other locations · NCT07912710

• Doll Therapy for Apathy and Daily Living in Older Adults with Dementia

  This study tests whether doll therapy helps reduce apathy and improves starting daily activities in older adults with dementia.

  Recruiting Guangzhou Medical University · Guangdong, Guangzhou · NCT07907042

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.