Multicenter study on acute type A aortic dissection
Official title: Nordic Multicenter Study of Risk Factors, Surgical Treatment and Outcomes in Acute Type A Aortic Dissection
Run by Karolinska Institutet · NCT06862583 · Data updated 2026-11-12
This study is trying to learn more about patients with acute type A aortic dissection by looking at their health details, surgeries, and recovery to see what affects their outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 5000 (estimated) |
| Sponsor | Karolinska Institutet Academic / other |
| Locations | 1 site (Stockholm) |
| Status | Recruiting |
| Started | June 3, 2019 |
| Main results expected | June 2029 |
| Study ends | June 2030 |
| Registry record updated | August 12, 2026 |
| Trial ID | NCT06862583 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients diagnosed with acute type A aortic dissection within 14 days of symptom onset.
✕Probably not a fit
Patients under 18 years of age will not benefit from this study as they are excluded from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The Nordic Consortium for Acute Type A Aortic Dissection-2 (NORCAAD-2) is a collaborative observational study involving multiple centers across the Nordic countries and the Netherlands. It aims to gather comprehensive data on patients with acute type A aortic dissection, focusing on preoperative characteristics, risk factors, surgical procedures, postoperative outcomes, and mortality rates over both short and long terms. By analyzing a large cohort of patients, the study seeks to enhance understanding of this critical vascular emergency and identify factors influencing outcomes.
Why it matters
Potential benefit: If successful, this study could improve patient management and outcomes for those suffering from acute type A aortic dissection.
How similar studies have gone: Other studies focusing on multicenter data collection for acute aortic dissection have shown promise in improving understanding and treatment outcomes.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Acute (within 14 days of onset) type A aortic dissection or similar acute aortic syndrome Exclusion Criteria: * Age \<18 years at onset
Where it's running
-
Karolinska Institute
Stockholm, Sweden Recruiting
Study contacts
- Principal investigator: Christian Olsson, MD, PhD — Karolinska Institutet
- Study coordinator: Christian Olsson, MD, PhD
- Email: christian.olsson@ki.se
- Phone: +46812370000
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Pregnancy-Related Aortic Dissection in China
This study looks at cases of aortic dissection that occur during pregnancy or shortly after, to understand outcomes for mothers and babies.
-
Ketorolac to improve outcomes and prognosis in Stanford Type A aortic dissection
This trial will test whether giving ketorolac around emergency surgery helps adults (18–65) with Stanford Type A aortic dissection recover better and have fewer complications over 90 days.
-
WeFlow-EndoPatch for Distal Aortic Tear Repair in Chronic Dissection
This study tests whether the WeFlow-EndoPatch Aortic Endovascular Patch can safely and effectively seal distal tears in chronic aortic dissection compared with standard treatment.
-
Aortic arch single-branch covered stent graft for treating aortic dissection
This trial tests a single-branch covered stent graft in adults with Stanford Type B aortic dissection who need revascularization of the left subclavian artery.
-
Shape‑memory polymer to seal the false lumen and prevent aortic enlargement
This trial will try a shape‑memory polymer implant to seal the false lumen and stop aortic growth in adults with type B dissection or treated type A dissection who need false lumen repair.
-
Using sivelestat to protect lung function after heart surgery
This study is testing if giving sivelestat to patients having emergency heart surgery can help protect their lungs and improve recovery by reducing serious complications.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.