Clinical trial Recruiting at 1 site Observational Ages 18 and up

Multicenter study on acute type A aortic dissection

Official title: Nordic Multicenter Study of Risk Factors, Surgical Treatment and Outcomes in Acute Type A Aortic Dissection

Run by Karolinska Institutet · NCT06862583 · Data updated 2026-11-12

This study is trying to learn more about patients with acute type A aortic dissection by looking at their health details, surgeries, and recovery to see what affects their outcomes.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment5000 (estimated)
SponsorKarolinska Institutet
Academic / other
Locations1 site (Stockholm)
StatusRecruiting
StartedJune 3, 2019
Main results expectedJune 2029
Study endsJune 2030
Registry record updatedAugust 12, 2026
Trial IDNCT06862583 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients diagnosed with acute type A aortic dissection within 14 days of symptom onset.

Probably not a fit

Patients under 18 years of age will not benefit from this study as they are excluded from participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The Nordic Consortium for Acute Type A Aortic Dissection-2 (NORCAAD-2) is a collaborative observational study involving multiple centers across the Nordic countries and the Netherlands. It aims to gather comprehensive data on patients with acute type A aortic dissection, focusing on preoperative characteristics, risk factors, surgical procedures, postoperative outcomes, and mortality rates over both short and long terms. By analyzing a large cohort of patients, the study seeks to enhance understanding of this critical vascular emergency and identify factors influencing outcomes.

Why it matters

Potential benefit: If successful, this study could improve patient management and outcomes for those suffering from acute type A aortic dissection.

How similar studies have gone: Other studies focusing on multicenter data collection for acute aortic dissection have shown promise in improving understanding and treatment outcomes.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Acute (within 14 days of onset) type A aortic dissection or similar acute aortic syndrome

Exclusion Criteria:

* Age \<18 years at onset

Where it's running

  • Karolinska Institute
    Stockholm, Sweden
    Recruiting

Study contacts

  • Principal investigator: Christian Olsson, MD, PhD — Karolinska Institutet
  • Study coordinator: Christian Olsson, MD, PhD
  • Email: christian.olsson@ki.se
  • Phone: +46812370000

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • Pregnancy-Related Aortic Dissection in China

    This study looks at cases of aortic dissection that occur during pregnancy or shortly after, to understand outcomes for mothers and babies.

    Recruiting at 4 sites DeltaHealth Hospital · Shanghai · Shanghai, Shanghai Municipality and 3 other locations · NCT07672210

  • Ketorolac to improve outcomes and prognosis in Stanford Type A aortic dissection

    This trial will test whether giving ketorolac around emergency surgery helps adults (18–65) with Stanford Type A aortic dissection recover better and have fewer complications over 90 days.

    Recruiting Phase 3 The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School · Nanjing, Jiangsu · NCT06968806

  • WeFlow-EndoPatch for Distal Aortic Tear Repair in Chronic Dissection

    This study tests whether the WeFlow-EndoPatch Aortic Endovascular Patch can safely and effectively seal distal tears in chronic aortic dissection compared with standard treatment.

    Recruiting Hangzhou Endonom Medtech Co., Ltd. · Beijing, Beijing Municipality · NCT06945809

  • Aortic arch single-branch covered stent graft for treating aortic dissection

    This trial tests a single-branch covered stent graft in adults with Stanford Type B aortic dissection who need revascularization of the left subclavian artery.

    Recruiting Lifetech Scientific (Shenzhen) Co., Ltd. · Changsha · NCT06915545

  • Shape‑memory polymer to seal the false lumen and prevent aortic enlargement

    This trial will try a shape‑memory polymer implant to seal the false lumen and stop aortic growth in adults with type B dissection or treated type A dissection who need false lumen repair.

    Recruiting at 2 sites Shape Memory Medical, Inc. · Auckland and 1 other locations · NCT06550986

  • Using sivelestat to protect lung function after heart surgery

    This study is testing if giving sivelestat to patients having emergency heart surgery can help protect their lungs and improve recovery by reducing serious complications.

    Recruiting at 2 sites Nanjing Medical University · Beijing and 1 other locations · NCT06195267

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.