Multicenter study on acute type A aortic dissection

Nordic Multicenter Study of Risk Factors, Surgical Treatment and Outcomes in Acute Type a Aortic Dissection

Observational Karolinska Institutet · NCT06862583

This study is trying to learn more about patients with acute type A aortic dissection by looking at their health details, surgeries, and recovery to see what affects their outcomes.

Quick facts

Study typeObservational
Enrollment5000 (estimated)
Ages18 Years and up
SexAll
SponsorKarolinska Institutet Academic / other
Locations1 site (Stockholm)
Trial IDNCT06862583 on ClinicalTrials.gov

What this trial studies

The Nordic Consortium for Acute Type A Aortic Dissection-2 (NORCAAD-2) is a collaborative observational study involving multiple centers across the Nordic countries and the Netherlands. It aims to gather comprehensive data on patients with acute type A aortic dissection, focusing on preoperative characteristics, risk factors, surgical procedures, postoperative outcomes, and mortality rates over both short and long terms. By analyzing a large cohort of patients, the study seeks to enhance understanding of this critical vascular emergency and identify factors influencing outcomes.

Who should consider this trial

Good fit: Ideal candidates for this study are patients diagnosed with acute type A aortic dissection within 14 days of symptom onset.

Not a fit: Patients under 18 years of age will not benefit from this study as they are excluded from participation.

Why it matters

Potential benefit: If successful, this study could improve patient management and outcomes for those suffering from acute type A aortic dissection.

How similar studies have performed: Other studies focusing on multicenter data collection for acute aortic dissection have shown promise in improving understanding and treatment outcomes.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Acute (within 14 days of onset) type A aortic dissection or similar acute aortic syndrome

Exclusion Criteria:

* Age \<18 years at onset

Where this trial is running

Stockholm

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Aortic DissectionOpen surgeryRisk factorsOutcomesMortalityCirculatory arrestcerebral protectionbicuspid aortic valve
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.