Motor and cognitive exercise program for Parkinson's disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In a randomized 1:1 feasibility trial, 48 people with Parkinson's disease and symptom duration of four or more years will be assigned to usual care or to a 12-week supervised exercise program plus usual care. The intervention includes treadmill gait and dual-task motor-cognitive training, progressive gait and balance exercises, and progressive lower-body resistance training delivered three times per week for one hour by a physiotherapist or exercise physiologist. Outcomes will be measured at baseline, 12 weeks, and at 6- and 12-month follow-up to capture short- and longer-term effects. The protocol was developed with the Copenhagen Trial Unit and detailed training protocols will be shared to support reproducibility.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of PD according to MDS-PD criteria
* Aged ≥ 18 years
* Informed consent
* PD symptoms ≥ 4 years
* Independent gait

Exclusion Criteria:

* Diagnosis of PD Dementia according to the MDS-PD Dementia criteria

Where it's running

• Department of Neurology, Bispebjerg and Frederiksberg Hospital
  Copenhagen NV, Denmark Recruiting

Study contacts

• Study coordinator: Annemette Løkkegaard, MD, PhD
• Email: annemette.loekkegaard@regionh.dk
• Phone: +45 38 63 52 48

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.