Monitoring mechanical energy in patients on mechanical ventilation
Protective Ventilation in Patients With Lung Impairment on Mechanical Ventilation Controlled by the Mechanical Energy of the Respiratory System
NA · University Hospital Ostrava · NCT06035146
This study is testing whether personalized ventilation settings based on monitored energy levels can help patients with acute respiratory failure avoid lung injury better than standard ventilation methods.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 34 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital Ostrava (other) |
| Locations | 1 site (Ostrava, Moravian-Silesian Region) |
| Trial ID | NCT06035146 on ClinicalTrials.gov |
What this trial studies
This project focuses on enhancing the monitoring of mechanical energy in patients undergoing mechanical ventilation due to acute respiratory failure. It aims to optimize ventilation settings to minimize lung injury caused by mechanical ventilation. Patients will be randomized into two groups: one receiving tailored mechanical ventilation based on monitored energy levels, and the other receiving standard ventilation practices. The study will also track routine laboratory values to assess patient condition.
Who should consider this trial
Good fit: Ideal candidates include adults over 18 with lung diseases such as pneumonia or ARDS who require mechanical ventilation for more than 48 hours.
Not a fit: Patients who are pregnant or those who have been on mechanical ventilation for more than 24 hours prior to study enrollment may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce lung injury and improve outcomes for patients with severe respiratory conditions.
How similar studies have performed: While the concept of monitoring mechanical energy is innovative, similar studies have shown promise in optimizing mechanical ventilation strategies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients with fully controlled mechanical ventilation * patients older than 18 years * patients with lung disease (pneumonia, ARDS) * expected duration of mechanical ventilation longer than 48 hours Exclusion Criteria: * pregnant women, when this fact is stated in the admission protocol * inclusion in the study in a period longer than 24 hours from the start of mechanical ventilation (from admission to the Anesthesiology and Resuscitation Department)
Where this trial is running
Ostrava, Moravian-Silesian Region
- University Hospital Ostrava — Ostrava, Moravian-Silesian Region, Czechia (RECRUITING)
Study contacts
- Principal investigator: Filip Burša, MD,PhD — University Hospital Ostrava
- Study coordinator: Jiří Hynčica
- Email: jiri.hyncica@fno.cz
- Phone: 0042059737
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: ARDS, Lung Injury, Ventilator Induced, mechanical ventilation, adult respiratory distress syndrome, ventilator-induced lung injury, mechanical energy