Mobile CBT for mood after a stroke

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot study tests an adapted mobile cognitive behavioral therapy app, Maya, in adults who recently had a stroke and are experiencing mood symptoms. Participants will use the app about 20 minutes per session, three days a week for five weeks, with content tailored to stroke recovery. The study focuses on acceptability, feasibility, and preliminary signals of efficacy within the acute rehabilitation period. Outcomes include mood and anxiety symptoms, functional recovery, and user engagement with the app. Eligibility requires recent stroke, adequate cognitive function, and ability to use an iPhone or iPad, with exclusion for language or neglect issues that would impede app use.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18-79
* Positive screen on the Hospital Anxiety and Depression Scale (HADS), either the HADSD (depression, score \>= 8) and/or HADS-A (anxiety, score \>= 8).
* Stroke that occurred within 1 month prior to study initiation.
* Capacity to provide consent as determined by the UCSD Brief Assessment for Capacity to Consent (UBACC)
* Montreal Cognitive Assessment (MoCA) score greater than or equal to 18, indicating no more than mild cognitive difficulties
* Ability to use iPhone or iPad independently or through the assistance of a caregiver (participants will use their own iPhone if they have one, otherwise they will be loaned an iPad by the study team)
* Able to adhere to all study requirements and willingness to participate in the full study duration

Exclusion Criteria:

* Aphasia or neglect that would interfere with use of the app, as determined through evaluation by speech-language pathology and occupational therapy conducted as part of standard clinical care
* Non-fluency in English
* History of a major neurologic disorder or of serious mental illness (bipolar or psychotic disorder, alcohol or substance use disorder as assessed through chart review)
* Active suicidal ideation requiring a higher level of care
* Severe depression and/or anxiety based on the initial evaluation and clinical judgment of the PI, which warrants a higher level of care and/or immediate referral to psychiatric services
* Any other clinical or medical reason in the initial evaluation that suggests the study is not appropriate for the participant

Where it's running

• Weill Cornell Medicine
  New York, New York, United States Recruiting

Study contacts

• Principal investigator: Abhishek Jaywant, PhD — Weill Medical College of Cornell University
• Study coordinator: Abhishek Jaywant, PhD
• Email: abj2006@med.cornell.edu
• Phone: 212-746-4666

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.