Behavioral health collaborative care for people recovering after ICU
Official title: Integration of a Behavioral Health Collaborative Care Model Into an ICU Recovery Clinic
Run by Medical University of South Carolina · NCT07372586 · Data updated 2026-11-12
This trial will test whether a coordinated behavioral health program using a digital app, coaching, and psychiatric support helps ICU survivors reduce anxiety, depression, and PTSD symptoms.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 150 (estimated) |
| Sponsor | Medical University of South Carolina Academic / other |
| Locations | 1 site (Charleston, South Carolina) |
| Status | Recruiting |
| Started | January 30, 2026 |
| Main results expected | June 30, 2028 |
| Study ends | June 30, 2028 |
| Registry record updated | March 12, 2026 |
| Trial ID | NCT07372586 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults seen in the MUSC ICU Recovery Clinic within 180 days of hospital discharge who have regular access to a smartphone, tablet, or computer and do not have excluded serious psychiatric or cognitive conditions are ideal candidates.
✕Probably not a fit
Patients with primary ICU admissions for addiction, serious mental illness (e.g., schizophrenia, acute mania), late-stage dementia, limited English or Spanish proficiency, or no regular internet-capable device are unlikely to benefit from this intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This single-site randomized controlled trial at the Medical University of South Carolina will enroll about 150 patients seen in the MUSC ICU Recovery Clinic and randomize them to a behavioral health Collaborative Care Model (BH CoCM) or an attention control group. The BH CoCM arm receives access to the NeuroFlow digital platform for six months plus behavioral health manager–led coaching and psychiatric support as needed, while the control arm receives regular assessments only. Investigators will measure changes in symptoms of anxiety, depression, and post-traumatic stress over six months, along with adherence, implementation metrics, and types of content used in NeuroFlow. Qualitative surveys will also be used to gather patient feedback on acceptability and ways to improve the intervention.
Why it matters
Potential benefit: If successful, the program could reduce symptoms of anxiety, depression, and PTSD and improve emotional recovery after critical illness.
How similar studies have gone: Collaborative Care Models have demonstrated effectiveness for depression and anxiety in other medical settings, but applying BH CoCM specifically to post-ICU recovery is relatively novel with limited prior randomized evidence.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: \- Attendance at the MUSC ICU Recovery Clinic within 180 days of discharge from the hospital Exclusion Criteria: * ICU Admission was due to a primary addiction diagnosis (eg alcohol withdrawal or delirium tremens requiring ICU care) * Serious Mental Illness such as Schizophrenia, psychotic disorder, acute mania * Late Stage Dementia or Cognitive Impairment * Limited English or Spanish Proficiency * Lack of regular access to a computer, tablet or mobile device with internet access
Where it's running
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Medical University of South Carolina
Charleston, South Carolina, United States Recruiting
Study contacts
- Principal investigator: Rita Bakhru, MD — Medical University of South Carolina
- Study coordinator: Rita Bakhru, MD
- Email: bakhru@musc.edu
- Phone: 8437924148
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.