Behavioral health collaborative care for family members of ICU survivors in the Post-ICU clinic pilot

Integration of a Behavioral Health Collaborative Care Model Into an ICU Recovery Clinic-Pilot for Families

Not applicable Interventional Medical University of South Carolina · NCT07390786

This pilot tests a telehealth-based behavioral health program using the NeuroFlow app for family members of ICU survivors to try to reduce anxiety, depression, and PTSD symptoms.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment150 (estimated)
Ages18 Years and up
SexAll
SponsorMedical University of South Carolina Academic / other
Locations1 site (Charleston, South Carolina)
Trial IDNCT07390786 on ClinicalTrials.gov

What this trial studies

Family members of patients seen in the MUSC ICU Recovery Clinic will be invited to participate and randomized to an intervention group or an attention control group. The intervention group will receive telehealth-enabled behavioral health assessments and six months of access to the NeuroFlow platform as part of a Behavioral Health Collaborative Care Model, while the control group will receive symptom assessments without NeuroFlow access. Investigators will measure changes in depression, anxiety, and post-traumatic stress symptoms over six months, plus adherence, implementation metrics, and the type and amount of guided content used in NeuroFlow. A subset of participants will complete qualitative interviews to capture acceptability and suggestions for improvement.

Who should consider this trial

Good fit: Ideal candidates are English-speaking family members of patients seen in the MUSC ICU Recovery Clinic who have an internet-enabled device and do not have serious mental illness or severe cognitive impairment.

Not a fit: People with serious mental illnesses (e.g., schizophrenia, mania), late-stage dementia, limited English proficiency, no internet-enabled device, or who are prisoners are excluded and unlikely to benefit from this intervention.

Why it matters

Potential benefit: If successful, this approach could reduce symptoms of anxiety, depression, and PTSD among family members of ICU survivors and increase access to coordinated behavioral care through telehealth.

How similar studies have performed: Collaborative care models and digital/telehealth behavioral interventions have shown benefit for depression and anxiety in other populations, but applying a BH CoCM specifically to family members of ICU survivors is relatively novel with mainly preliminary evidence.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

\- Family member of ICU Recovery Clinic patient enrolled in parent BH CoCM study

Exclusion Criteria:

* Serious mental illness (e.g., schizophrenia, mania)
* Late-stage dementia or cognitive impairment
* Limited English proficiency
* No internet-enabled device
* Prisoners

Where this trial is running

Charleston, South Carolina

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Critical Illness RecoveryBehavioral Health ConcernsAnxietyDepression - Major Depressive DisorderPTSDCritical Care, Intensive CarePICS-FCritical Ilness
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.