Analyzing CGRP Levels in Migraine Patients by Age and Sex

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the levels of CGRP, a neuropeptide associated with migraine, in patients diagnosed with migraines and healthy controls. Participants will visit the study center twice: first for a clinical assessment and then for the collection of blood and saliva samples. The study will measure CGRP levels in saliva and conduct DNA and hormone testing from blood samples to explore differences in treatment responses based on sex and age. The findings may provide insights into the biological underpinnings of migraines.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Migraine patients according to ICHD-3 criteria
* Healthy controls paired to patient age and sex, without headache and without first degree family history of headache.

Exclusion Criteria:

* Presence of any major medical or neurological illness.
* Presence of any salivary gland malfunction.
* Abuse or dependence to tobacco, alcohol or any drug in the previous 12 months before the enrollment.
* Active migraine preventive treatment.
* Pregnant or breastfeeding female.

Where it's running

• Vall d'Hebron University Hospital
  Barcelona, Barcelona, Spain Recruiting

Study contacts

• Study coordinator: Patricia Pozo-Rosich, MD, PhD
• Email: ppozo@vhebron.net
• Phone: (+34)934893000

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Evaluating the effectiveness of rimegepant for preventing migraines

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• Evaluating the effectiveness of rimegepant for treating migraines

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  Recruiting at 2 sites University of Florence · Florence and 1 other locations · NCT05903027

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.