Minimally Invasive Injectable Platelet Concentrate for Deep Pockets in Periodontitis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study evaluates a minimally invasive non-surgical approach combined with injectable platelet concentrate for treating intrabony periodontal defects in adults with stage III–IV periodontitis. Eligible participants have at least one intrabony defect (≥3 mm radiographic depth) and a pocket depth of 6 mm or more, after initial therapy. The procedure involves delivering injectable platelet concentrate alongside a MINST technique, with follow-up through 6 months to assess pocket depth changes. Participants must be non-smokers or never-smokers and able to consent and complete follow-up. There is no listed funding from multiple centers; Cairo University leads the trial in Cairo, Egypt.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with periodontitis stage III-IV.
* Presence of at least one intrabony defect with radiographic component ≥ 3mm deep and PPD≥ 6mm (not affecting a tooth with 'hopeless' prognosis).
* Patients willing to sign informed consent and to be in the study until the 6-months follow-up.
* Full-mouth plaque score \<30% following step 1 periodontal therapy

Exclusion Criteria:

* Smoker/vaper (currently or in past 5 years).
* Contributory medical history (e.g. cardiovascular disease, diabetes, psychiatric conditions).

Where it's running

• Cairo University
  Cairo, Egypt Recruiting

Study contacts

• Study coordinator: Hania Haggag
• Email: hania.haggag@dentistry.cu.edu.eg
• Phone: +01210239417

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.