Mindfulness program to improve quality of life in patients with drug-resistant epilepsy
Official title: Impact of Mindfulness Intervention on Quality of Life in Patients With Drug-resistant Epilepsy.
Run by University Hospital, Grenoble · NCT04126369 · Data updated 2026-11-12
This study is testing whether a mindfulness program can help improve the quality of life for people with drug-resistant epilepsy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | University Hospital, Grenoble Academic / other |
| Locations | 3 sites (Grenoble and 2 other locations) |
| Status | Recruiting |
| Started | January 20, 2020 |
| Main results expected | January 20, 2026 |
| Study ends | September 20, 2027 |
| Registry record updated | May 8, 2024 |
| Trial ID | NCT04126369 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals diagnosed with drug-resistant epilepsy who have stable therapy and are not currently practicing mindfulness.
✕Probably not a fit
Patients with psychogenic non-epileptic seizures or those who have previously practiced mindfulness may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of a mindfulness intervention in improving the quality of life for patients suffering from drug-resistant epilepsy. Participants will be randomly assigned to either a mindfulness program or a psychoeducative self-management program, with both interventions lasting three months. The study includes a two-month baseline assessment followed by a six-month post-intervention follow-up to evaluate changes in emotional management and quality of life. Participants will also maintain a daily log of their seizures and emotional state throughout the study.
Why it matters
Potential benefit: If successful, this intervention could significantly enhance the quality of life for patients with drug-resistant epilepsy by improving their emotional well-being.
How similar studies have gone: Other studies have shown promising results using mindfulness interventions for chronic conditions, suggesting potential success for this approach in epilepsy management.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Drug resistant epilepsy according to the criteria of the International League Against Epilepsy (ILAE) * Stable therapy for at least 3 months * No planned surgery * Patient affiliated to social security insurance or beneficiary of social security insurance. * Signed consent Exclusion Criteria: * Patient who has previously had or regularly practicing mindfulness * Patient with psychogenic non-epileptic seizures * Pregnant woman, breastfeeding mother, person deprived of liberty by judicial or administrative decision, person subject to legal protection * Patient with relationship disorders related to psychosis * Patients who are unable or unwilling to work as a group or person unable to understand the topics discussed during session.
Where it's running
-
Epileptology Department of The Grenoble University Hospital
Grenoble, France Recruiting -
Epileptology Department of the Lyon University Hospital
Lyon, France Not yet recruiting -
La Teppe medical centre
Tain-l'Hermitage, France Not yet recruiting
Study contacts
- Study coordinator: Cécile SABOURDY, MD
- Email: CSabourdy@chu-grenoble.fr
- Phone: 04767656.9
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Modified ketogenic diet for adults with drug-resistant epilepsy
This study tests whether a modified ketogenic diet can help adults with drug-resistant epilepsy see fewer seizures and feel better overall.
-
Non-Invasive Low Intensity Focused Ultrasound Stimulation for Drug-Resistant Epilepsy
This study tests whether low intensity focused ultrasound can help reduce seizures in adults with drug‑resistant epilepsy.
-
iVEAcare Neuromodulation System for drug‑resistant epilepsy: a feasibility look
This study tests whether the iVEAcare neuromodulation system is safe and can help reduce seizures and improve quality of life in people with drug‑resistant epilepsy.
-
Real-world use of the OneRF Ablation System for epilepsy
This registry collects real-world outcomes and device performance from patients with drug-resistant epilepsy who are treated with SEEG-guided RF ablation using the OneRF system.
-
Overnight Temporal Interference Stimulation for Temporal Lobe Epilepsy
This study tests whether overnight, non-invasive temporal interference stimulation to the hippocampus can reduce seizure-related brain activity and improve sleep in adults with drug-resistant temporal lobe epilepsy.
-
Biomarkers of Response to SEEG Thermocoagulation
This study tests biomarkers to see if they predict how well SEEG-guided radiofrequency thermocoagulation helps people with drug-resistant focal epilepsy.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.