Mindfulness program to improve quality of life in patients with drug-resistant epilepsy

Impact of Mindfulness Intervention on Quality of Life in Patients With Drug-resistant Epilepsy.

Not applicable Interventional University Hospital, Grenoble · NCT04126369

This study is testing whether a mindfulness program can help improve the quality of life for people with drug-resistant epilepsy.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment100 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity Hospital, Grenoble Academic / other
Locations3 sites (Grenoble and 2 other locations)
Trial IDNCT04126369 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of a mindfulness intervention in improving the quality of life for patients suffering from drug-resistant epilepsy. Participants will be randomly assigned to either a mindfulness program or a psychoeducative self-management program, with both interventions lasting three months. The study includes a two-month baseline assessment followed by a six-month post-intervention follow-up to evaluate changes in emotional management and quality of life. Participants will also maintain a daily log of their seizures and emotional state throughout the study.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals diagnosed with drug-resistant epilepsy who have stable therapy and are not currently practicing mindfulness.

Not a fit: Patients with psychogenic non-epileptic seizures or those who have previously practiced mindfulness may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly enhance the quality of life for patients with drug-resistant epilepsy by improving their emotional well-being.

How similar studies have performed: Other studies have shown promising results using mindfulness interventions for chronic conditions, suggesting potential success for this approach in epilepsy management.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Drug resistant epilepsy according to the criteria of the International League Against Epilepsy (ILAE)
* Stable therapy for at least 3 months
* No planned surgery
* Patient affiliated to social security insurance or beneficiary of social security insurance.
* Signed consent

Exclusion Criteria:

* Patient who has previously had or regularly practicing mindfulness
* Patient with psychogenic non-epileptic seizures
* Pregnant woman, breastfeeding mother, person deprived of liberty by judicial or administrative decision, person subject to legal protection
* Patient with relationship disorders related to psychosis
* Patients who are unable or unwilling to work as a group or person unable to understand the topics discussed during session.

Where this trial is running

Grenoble and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Drug Resistant Epilepsymindfulnessself management
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.