Mindfulness plus dual-task training for people after stroke with mild cognitive impairment
Official title: Mindfulness Combined With Dual-Task Training for Post-Stroke Mild Cognitive Impairment: A Randomized Controlled Trial
Run by Nanjing Mingzhou Rehabilitation Hospital · NCT07603102 · Data updated 2026-11-12
This study tests whether combining mindfulness with dual-task training can help improve thinking skills and physical function in people who recently had a stroke and have mild cognitive impairment.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 55 Years and up |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Nanjing Mingzhou Rehabilitation Hospital Academic / other |
| Locations | 1 site (Nanjing) |
| Status | Recruiting |
| Started | May 1, 2026 |
| Main results expected | November 2026 |
| Study ends | November 2026 |
| Registry record updated | May 22, 2026 |
| Trial ID | NCT07603102 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults who are at least 3 months post-stroke, have MoCA < 26 and MMSE ≥ 24, and can walk 10 meters with or without an aid, with stable medications and the ability to consent.
✕Probably not a fit
Individuals with severe aphasia, significant visual or hearing impairments, major psychiatric disorders, or other neurological conditions affecting cognition or movement may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study explores a combined intervention of mindfulness, dual-task training, aerobic training, and health education for individuals with post-stroke mild cognitive impairment. Enrolled participants must be at least 3 months post-stroke, have MoCA scores below 26 and MMSE scores at least 24, and be able to walk 10 meters with or without an aid. The approach seeks to determine if the integrated program can enhance cognitive performance and physical capabilities compared to standard care. The study is based at Nanjing Mingzhou Rehabilitation Hospital in Nanjing, China, with inclusive criteria focusing on stable health status and the ability to participate in training sessions.
Why it matters
Potential benefit: If successful, the program could lead to improved cognition and mobility for stroke survivors with mild cognitive impairment.
How similar studies have gone: Previous research suggests that mindfulness and physical training can benefit cognitive and functional outcomes, but the added dual-task and combined approach is relatively novel in this exact post-stroke MCI population.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of stroke confirmed by computed tomography (CT) or magnetic resonance imaging (MRI). * Time since stroke onset ≥3 months and medically stable. * Presence of mild cognitive impairment after stroke, defined by a Montreal - - Montreal Cognitive Assessment (MoCA) score \< 26. * Mini-Mental State Examination (MMSE) score ≥ 24. * Ability to walk independently with or without an assistive device for at least 10 meters. * Stable medication regimen for at least 4 weeks prior to enrollment. * Ability to understand study instructions and provide written informed consent. Exclusion Criteria: * Severe aphasia, visual impairment, hearing impairment, or communication disorders that interfere with assessment or training participation. * Severe depression or other major psychiatric disorders. * Other neurological diseases affecting cognition or movement (e.g., Parkinson's disease, multiple sclerosis, traumatic brain injury). * Severe musculoskeletal, cardiovascular, or systemic diseases that contraindicate exercise participation. * Participation in other structured cognitive or rehabilitation intervention programs within the past 3 months. * Unstable medical condition or recurrent stroke during the study period. * Inability to safely complete the training protocol as determined by the study investigators.
Where it's running
-
Nanjing Mingzhou Rehabilitation Hospital
Nanjing, China Recruiting
Study contacts
- Study coordinator: Jingzhi Zhang
- Email: 170787717@qq.com
- Phone: +86-16677137704
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.