Milled vs 3D-Printed Partial-Coverage Restorations in Endodontically Treated Molars

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial compares two fabrication methods for indirect composite resin restorations (onlays/overlays) in endodontically treated molars. All restorations are made using a fully digital workflow, with standardized tooth preparation, bonding, and cementation, and follow-up visits at 12, 24, and 36 months. Outcomes will include survival, success rates, and potential complications, using internationally accepted criteria. The study takes place at Hospital San José in Santiago, Chile, and uses commercially available materials from additive and subtractive manufacturing. The goal is to determine if 3D-printed restorations can provide clinical results comparable to milled restorations over medium-term follow-up.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18 to 70 years
* Absence of active periodontal disease
* Good oral hygiene (O'Leary plaque index \<20%)
* Absence of parafunctional habits (e.g., bruxism, onychophagia)
* Endodontically treated first molars (maxillary or mandibular) with extensive Class II cavities and loss of at least one cusp, requiring onlay or overlay restoration
* Tooth with functional occlusal contact and at least one proximal contact
* Referred from the Endodontics Department of Hospital San José, with endodontic treatment completed at the same institution
* Ability to provide written informed consent
* Ability to attend follow-up visits at 12, 24, and 36 months

Exclusion Criteria:

* Untreated active periodontal disease
* Poor oral hygiene (O'Leary plaque index ≥20%)
* Generalized active caries
* Active parafunctional habits
* Teeth with complete circumferential structural destruction or insufficient coronal tooth structure for onlay/overlay restoration
* Subgingival margins compromising the biologic width
* Known allergy to study materials
* Pregnancy or breastfeeding

Where it's running

• Hospital San José
  Santiago, Santiago Metropolitan, Chile Recruiting

Study contacts

• Principal investigator: Tomás Yoma Galleguillos, DDS — Hospital San José, Santiago, Chile
• Study coordinator: Tomás Yoma Galleguillos, DDS
• Email: tomasyoma@gmail.com
• Phone: +56985768407

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.