3D-printed hybrid resin versus CAD/CAM composite overlays for endodontically treated molars

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized trial at the University Dental Clinic of the Universitat Internacional de Catalunya will enroll 60 patients needing an indirect adhesive overlay on an endodontically treated molar. Participants are randomly assigned to receive restorations made either from a 3D-printed hybrid resin (VarseoSmile TriniQ) or a CAD/CAM composite block (Cerasmart), with each material group further randomized to cementation with either a preheated microhybrid composite (Enamel Plus HRi) or a resin cement (RelyX Universal). All restorations are produced using a digital workflow including intraoral scanning, CAD design, and either additive (3D printing) or subtractive (milling) manufacturing, followed by adhesive cementation per the assigned protocol. Clinical performance and any complications will be recorded at follow-up visits to compare materials and luting protocols.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥18 years
* Signed informed consent
* Need to restore an endodontically treated molar with an indirect adhesive overlay
* Physically and psychologically able to tolerate conventional restorative procedures
* No high caries risk
* No active periodontal disease
* Natural antagonist tooth present
* Need for full cuspal coverage restoration (overlay)
* Remaining wall thickness \<3 mm in the endodontically treated tooth
* Occlusal thickness of the restoration ≥1 mm
* Willing and able to attend follow-up visits

Exclusion Criteria:

* Poor oral hygiene
* Uncontrolled parafunctional habits (e.g., bruxism)
* High caries risk
* Active periodontal disease
* Active pulpal disease
* Absence of natural antagonist tooth
* Need for partial cuspal coverage restoration (inlay or onlay)
* Insufficient interarch space for restoration
* Teeth planned as abutments for removable or fixed prostheses
* Known allergy to any materials used in the study

Where it's running

• Clínica Universitària d'Odontologia UIC Barcelona
  Sant Cugat del Vallès, Barcelona, Spain Recruiting

Study contacts

• Principal investigator: Marta Valles — Universitat Internacional de Catalunya
• Study coordinator: MARTA VALLES, DDS, PhD
• Email: mvalles@uic.es
• Phone: +34619747903

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.