Evaluating the success of different root canal sealers in dental treatment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study is a prospective randomized controlled trial that aims to assess the success rates of endodontic treatment and retreatment using two different root canal sealers: BioRoot™ RCS and AH Plus. Patients diagnosed with irreversible pulpitis or apical periodontitis will be enrolled and followed for up to six years to compare the effectiveness of these sealers. The study will test the hypothesis that there are no significant differences in treatment success rates between the two sealers. Participants will be required to provide informed consent and meet specific eligibility criteria.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients that demonstrate understanding of the study and willingness to participate as evidenced by signing the voluntary informed consent and received a signed and dated copy of the informed consent form.
* Understands and is willing to comply with all study procedures and restrictions.
* Not presence of clinically significant and relevant abnormalities of clinical history or oral examination.
* Diagnosis of irreversible pulpitis or apical symptomatic / asymptomatic periodontitis.
* Retreatment cases due to an endodontic failure.
* Single or bi-radicular teeth.

Exclusion Criteria:

* General: Patients with systemic diseases, diabetes, immunocompromised and pregnant women, or any clinically significant or relevant oral abnormalities.
* Specific: root resorption, root fractures, impossibility of restoration and cases were primary or secondary root canal treatment is not the treatment of choice.

Where it's running

• Universitat Internacional de Catalunya
  Sant Cugat del Vallès, Barcelona, Spain Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.