Metabolomics biomarkers to predict outcomes after subarachnoid hemorrhage

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a single-center, prospective observational study of adults with acute spontaneous SAH admitted to a neurocritical care unit in Lisbon. Researchers collect blood and cerebrospinal fluid samples on days 1, 3 and 7 and combine metabolomic data with clinical scales, imaging, neuromonitoring, and routine labs to develop a prognostic model for long-term outcome. The goal is to identify metabolites linked to death or long-term disability and see if a predictive model can forecast recovery one year after discharge. Participants receive standard medical care; the study does not modify treatment decisions. Techniques include FT-IR spectroscopy as a potential low-cost method to translate findings into clinical practice.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 years or older
* Diagnosis of acute spontaneous (non-traumatic) subarachnoid hemorrhage
* Admission to the Neurocritical Care and Trauma Unit of ULS São José

Exclusion Criteria:

* Traumatic subarachnoid hemorrhage
* Death before ICU admission
* Refusal of informed consent by the patient or legal representative

Where it's running

• Unidade Local de Saude Sao Jose
  Lisbon, Lisbon District, Portugal Recruiting

Study contacts

• Study coordinator: Bruno Maia, MD
• Email: bruno.maia@ulssjose.min-saude.pt
• Phone: +351 962192079

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.