AI-based EEG for better stroke and post-cardiac arrest outcomes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study develops AI algorithms that analyze subhairline EEG data to predict neurological outcomes in adults with postanoxic coma after cardiac arrest and to detect intracranial hemorrhage in adults with suspected stroke or SAH. Participants will receive a continuous subhairline EEG patch in addition to standard care EEG where applicable. The study aims to validate AI models for outcome prediction at around 24 hours after cardiac arrest and for hemorrhage detection using EEG and clinical information. The approach seeks to enable faster, noninvasive assessment in critical care and emergency settings.

Why it matters

Who can join: the full rules

Inclusion Criteria:

All participants:

\- Age 18 years or older

Postanoxic coma (ICU):

* Postanoxic coma after cardiac arrest, admitted to the intensive care unit
* No objection to participation within 4 weeks of receiving an opt-out information letter

Suspected stroke (emergency department):

* Suspected stroke as assessed by the ambulance personnel presenting the patient to the emergency department, or confirmed stroke.
* Symptom onset, or last seen well if onset was not witnessed, less than 24 hours ago.
* Written (deferred) informed consent by the patient or legal representative

Suspected subarachnoid hemorrhage (emergency department):

* Suspected subarachnoid hemorrhage as judged by the attending ambulance paramedic, or confirmed subarachnoid hemorrhage.
* Symptom onset, or last seen well if onset was not witnessed, less than 48 hours ago.
* Written (deferred) informed consent by the patient or legal representative.

Exclusion Criteria:

All participants:

\- (Suspected) skin damage or infection at the placement area of the subhairline EEG patch

Postanoxic coma (ICU):

\- Other types of severe brain injury, either pre-existing or coinciding with cardiac arrest. These include stroke, traumatic brain injury and progressive neurodegenerative disease.

Where it's running

• Amsterdam University Medical Center
  Amsterdam, North Holland, Netherlands Recruiting

Study contacts

• Study coordinator: Kars Tjepkema
• Email: k.r.tjepkema@amsterdamumc.nl
• Phone: 0031644761222

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.